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Table 1 The associations of NNMT expression with OS in GSE9891 dataset

From: Patients with low nicotinamide N-methyltransferase expression benefit significantly from bevacizumab treatment in ovarian cancer

Variables

Number of patients

Univariate analysis

Multivariate analysis

HR (95%CI)

P value

HR (95%CI)

P value

Age

242

1.029 (1.008–1.051)

0.006

1.031 (1.009–1.053)

0.005

Stage

  

0.002

 

0.012

 Early

37

1

 

1

 

 Late

205

6.315 (1.997–19.963)

 

4.444 (1.379–14.322)

 

Grade

  

0.142

 

/

 Low

99

1

 

/

 

 High

143

1.365 (0.901–2.068)

 

/

 

Debulking

  

0.005

 

0.054

 Optimal

158

1

 

1

 

 Suboptimal

84

1.770 (1.190–2.633)

 

1.494 (0.993–2.249)

 

NNMT expression

  

< 0.001

 

0.002

 Low

176

1

 

1

 

 High

66

2.278 (1.513–3.430)

 

1.914 (1.265–2.894)