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Table 4 Analysis of association of TGM2 polymorphism (rs4811528) with the development of DS in APL patients

From: The impact of ICAM-1, CCL2 and TGM2 gene polymorphisms on differentiation syndrome in acute promyelocytic leukemia

Model

Genotype

DS (%)

No DS (%)

OR (95% CI)

P-value

AIC

BIC

Codominant

A/A

13 (72.2)

37 (32.2)

1.00

0.0096

90.2

104.7

A/G

4 (22.2)

54 (47)

5.61 (1.53–20.48)

G/G

1 (5.6)

24 (20.9)

6.14 (0.70–53.45)

Dominant

A/A

13 (72.2)

37 (32.2)

1.00

0.0023

88.2

99.8

A/G-G/G

5 (27.8)

78 (67.8)

5.72 (1.74–18.81)

Recessive

A/A-A/G

17 (94.4)

91 (79.1)

1.00

0.24

96.2

107.7

G/G

1 (5.6)

24 (20.9)

3.03 (0.36–25.25)

Over dominant

A/A-G/G

14 (77.8)

61 (53)

1.00

0.02

92.1

103.6

A/G

4 (22.2)

54 (47)

4.06 (1.14–14.44)

Log-additive

3.78 (1.37–10.44)

0.004

89.2

100.8

  1. AIC Akaike Information criterion, BIC Bayesian Information