Table 2 Univariate and multivariate analysis
From: Value of digital mammography in predicting lymphovascular invasion of breast cancer
Factors | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | |
Interstitial edema | 4.471(1.260,15.864) | 0.020 | 12.610(1.061,149.922) | 0.045 |
Subcutaneous fat | 1.213(0.458,3.207) | 0.698 | 0.081(0.012,0.645) | 0.017 |
Thicken Skin | 4.333(1.899,9.891) | 0.000 | 9.041(2.553,32.022) | 0.001 |
ER | 0.475(0.216,1.044) | 0.064 | 1.595(0.252,10.084) | 0.62 |
PR | 0.481(0.224,1.034) | 0.061 | 0.508(0.085,3.035) | 0.458 |
HER-2 | 1.003(0.429,2.345) | 0.994 | 1.436(0.462,4.466) | 0.532 |
Ki-67 | ||||
Moderate | 0.690(0.209,2.273) | 0.541 | 0.382(0.094,1.551) | 0.178 |
High | 2.581(0.948,7.022) | 0.063 | 1.298(0.350,4.809) | 0.696 |
P53 | 1.920(0.827,4.457) | 0.129 | 2.115(0.739,6.050) | 0.163 |
Amount of fibroglandular tissue | ||||
Heterogeneous fibroglandular tissue | 0.948(0.414,2.179) | 0.899 | 1.439(0.491,4.215) | 0.507 |
Extreme fibroglandular tissue | 1.856(0.630,5.469) | 0.262 | 3.773(0.707,20.154) | 0.12 |
Size | 1.928(0.890,4176) | 0.096 | 0.921(0.294,2.891) | 0.889 |
Nipple retraction | 2.267(0.914,5.621) | 0.077 | 1.299(0.281,5.991) | 0.738 |
Single/multiple | 1.158(0.476,2.819) | 0.746 | 1.183(0.336,4.165) | 0.793 |
Lesions | 1.057(0.500,2.233) | 0.885 | 0.712(0.256,1.979) | 0.514 |
Mass shape | 0.472(0.163,1.365) | 0.166 | 0.624(0.128,3.047) | 0.56 |
Margin | 0.224(0.043,1.389) | 0.112 | 0.424(0.032,5.630) | 0.516 |
Boundary | ||||
Obscure | 1.469(0.586,3.684) | 0.413 | 1.483(0.439,5.007) | 0.526 |
Shield | 1.131(0.436,2.935) | 0.800 | 0.997(0.246,4.043) | 0.997 |
Axillary lymph node enlargement | 1.716(0.797,3.694) | 0.168 | 0.909(0.295,2.805) | 0.868 |
E-cad | 0.250(0.043,1.452) | 0.122 | ||
Location | ||||
Outer lower | 0.510(0.054,4.819) | 0.557 | ||
Lower inner | 1.021(0.314,3.320) | 0.973 | ||
Upper inner | 1.361(0.434,4.267) | 0.597 | ||
Central area | 1.531(0.477,4.913) | 0.474 | ||
Calcification | 1.857(0.601,5.734) | 0.166 | ||
Family history | 1.927(0.117,31.602) | 0.646 | ||
History of giving birth | 2.158(0.233,19.947) | 0.498 | ||
History of abortion | 0.781(0.339,1.799) | 0.561 | ||
CA15–3 | 1.925(0.261,14.179) | 0.52 | ||
History of related illness | 0.463(0.050,4.284) | 0.498 | ||