Table 1 Patient characteristics
Total N = 10,325 | Resection | Metastasis | |||||||
|---|---|---|---|---|---|---|---|---|---|
No Resection N = 7419 | Resection N = 2906 | Pa | Liver N = 8195 | Lung N = 807 | Both N = 1323 | Pa | |||
Resection | No | 7419 (71.9%) | 7419 (100%) | – | – | 5695 (69.5%) | 663 (82.2%) | 1061 (80.2%) | < 0.001 |
Yes | 2906 (28.1%) | – | 2906 (100%) | 2500 (30.5%) | 144 (17.8%) | 262 (19.8%) | |||
Metastasis | Liver only | 8195 (79.4%) | 5695 (76.8%) | 2500 (86.0%) | < 0.001 | 8195 (100%) | – | – | – |
Lung only | 807 (7.8%) | 663 (8.9%) | 144 (5.0%) | – | 807 (100%) | – | |||
Liver and Lung | 1323 (12.8%) | 1061 (14.3%) | 262 (9.0%) | – | – | 1323 (100%) | |||
Tumor localization | Right colon | 3485 (33.8%) | 2602 (35.1%) | 883 (30.4%) | < 0.001 | 2808 (34.3%) | 220 (27.3%) | 457 (34.5%) | < 0.001 |
Transverse | 1401 (13.6%) | 1005 (13.5%) | 396 (13.6%) | 1140 (13.9%) | 98 (12.1%) | 163 (12.3%) | |||
Left colon | 3311 (32.1%) | 2346 (31.6%) | 965 (33.2%) | 2666 (32.5%) | 231 (28.6%) | 414 (31.3%) | |||
Rectosigmoid | 966 (9.4%) | 680 (9.2%) | 286 (9.8%) | 736 (9.0%) | 88 (10.9%) | 142 (10.7%) | |||
Rectum | 1162 (11.3%) | 786 (10.6%) | 376 (12.9%) | 845 (10.3%) | 170 (21.1%) | 147 (11.1%) | |||
T-Stage | T1 to T3 | 6643 (64.3%) | 4727 (63.7%) | 1916 (65.9%) | 0.034 | 5348 (65.3%) | 532 (65.9%) | 763 (57.7%) | < 0.001 |
T4 | 3682 (35.7%) | 2692 (36.3%) | 990 (34.1%) | 2847 (34.7%) | 275 (34.1%) | 560 (42.3%) | |||
N-Stage | N0 | 2103 (20.4%) | 1439 (19.4%) | 664 (22.8%) | < 0.001 | 1654 (20.2%) | 230 (28.5%) | 219 (16.6%) | < 0.001 |
N+ | 8222 (79.6%) | 5980 (80.6%) | 2242 (77.2%) | 6541 (79.8%) | 577 (71.5%) | 1104 (83.4%) | |||
Grade | G1/2 | 7715 (74.7%) | 5450 (73.5%) | 2265 (77.9%) | < 0.001 | 6090 (74.3%) | 615 (76.2%) | 1010 (76.3%) | 0.118 |
G3/4 | 2610 (25.3%) | 1969 (26.5%) | 641 (22.1%) | 2105 (25.7%) | 192 (23.8%) | 313 (23.7%) | |||
Chemo- and/or | No | 2842 (27.5%) | 2294 (30.9%) | 548 (18.9%) | < 0.001 | 2216 (27.0%) | 235 (29.1%) | 391 (29.6%) | 0.437 |
Radiotherapy | Yes | 7483 (72.5%) | 5125 (69.1%) | 2358 (81.1%) | 5979 (73.0%) | 572 (70.9%) | 932 (70.4%) | ||
Year of diagnosis | 2010–2012 | 5304 (51.4%) | 3915 (52.8%) | 1389 (47.8%) | < 0.001 | 4279 (52.2%) | 365 (45.2%) | 660 (49.9%) | 0.005 |
2013–2015 | 5021 (48.6%) | 3504 (47.2%) | 1517 (52.2%) | 3916 (47.8%) | 442 (54.8%) | 663 (50.1%) | |||
Age (years) | < 50 | 1799 (17.4%) | 1130 (15.2%) | 669 (23.0%) | < 0.001 | 1474 (18.0%) | 120 (14.9%) | 205 (15.5%) | 0.005 |
50–64 | 4065 (39.4%) | 2843 (38.3%) | 1222 (42.1%) | 3241 (39.5%) | 285 (35.3%) | 539 (40.7%) | |||
65–79 | 3247 (31.4%) | 2448 (33.0%) | 799 (27.5%) | 2525 (30.8%) | 285 (35.3%) | 437 (33.0%) | |||
80+ | 1214 (11.8%) | 998 (13.5%) | 216 (7.4%) | 955 (11.7%) | 117 (14.5%) | 142 (10.7%) | |||
Gender | Male | 5693 (55.1%) | 4159 (56.1%) | 1534 (52.8%) | 0.003 | 4585 (55.9%) | 387 (48.0%) | 721 (54.5%) | 0.003 |
Female | 4632 (44.9%) | 3260 (43.9%) | 1372 (47.2%) | 3610 (44.1%) | 420 (52.0%) | 602 (45.5%) | |||
Ethnicity | Caucasian | 7787 (75.4%) | 5576 (75.2%) | 2211 (76.1%) | 0.336 | 6237 (76.1%) | 591 (73.2%) | 959 (72.5%) | 0.117 |
African-American | 1555 (15.1%) | 1117 (15.1%) | 438 (15.1%) | 1219 (14.9%) | 115 (14.3%) | 221 (16.7%) | |||
Other/Unknown | 983 (9.5%) | 726 (9.8%) | 257 (8.8%) | 739 (9.0%) | 101 (12.5%) | 143 (10.8%) | |||
Marital status | Married | 5583 (54.1%) | 3925 (52.9%) | 1658 (57.1%) | < 0.001 | 4501 (54.9%) | 399 (49.4%) | 683 (51.6%) | 0.061 |
Single/Widowed | 3057 (29.6%) | 2256 (30.4%) | 801 (27.6%) | 2398 (29.3%) | 259 (32.1%) | 400 (30.2%) | |||
Other/Unknown | 1685 (16.3%) | 1238 (16.7%) | 447 (15.4%) | 1296 (15.8%) | 149 (18.5%) | 240 (18.1%) | |||