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Table 1 Patient characteristics

From: Mutation landscape of germline and somatic BRCA1/2 in patients with high-grade serous ovarian cancer

 

Overall BRCAm (n = 24)

BRCAw

(n = 74)

P

Germline BRCAm (n = 17)

Only Somatic BRCAm (n = 7)

Age

53 (42–74)

54 (48–77)

56 (22–78)

0.353

Stage

 I

0

0

1 (1.4)

0.838

 II

1 (5.9)

0

3 (4.1)

 

 III

7 (41.2)

3 (42.9)

35 (47.3)

 

 IV

9 (52.9)

4 (57.1)

35 (47.3)

 

Breast cancer

2 (11.8)

0

1 (1.4)

0.084

BRCA-related FHx

4 (23.5)

3 (42.9)

9 (12.2)

0.05

NGR

10 (58.8)

6 (85.7)

42 (56.8)

0.39

NAC

10 (58.8)

4 (57.1)

32 (43.2)

0.242

  1. BRCAm BRCA mutation, BRCAw BRCA wild type, FHx family history, NGR no gross residual disease, NAC neoadjuvant chemotherapy