Skip to main content

Table 1 Patient characteristics

From: Mutation landscape of germline and somatic BRCA1/2 in patients with high-grade serous ovarian cancer

 Overall BRCAm (n = 24)BRCAw
(n = 74)
P
Germline BRCAm (n = 17)Only Somatic BRCAm (n = 7)
Age53 (42–74)54 (48–77)56 (22–78)0.353
Stage
 I001 (1.4)0.838
 II1 (5.9)03 (4.1) 
 III7 (41.2)3 (42.9)35 (47.3) 
 IV9 (52.9)4 (57.1)35 (47.3) 
Breast cancer2 (11.8)01 (1.4)0.084
BRCA-related FHx4 (23.5)3 (42.9)9 (12.2)0.05
NGR10 (58.8)6 (85.7)42 (56.8)0.39
NAC10 (58.8)4 (57.1)32 (43.2)0.242
  1. BRCAm BRCA mutation, BRCAw BRCA wild type, FHx family history, NGR no gross residual disease, NAC neoadjuvant chemotherapy