From: Mutation landscape of germline and somatic BRCA1/2 in patients with high-grade serous ovarian cancer
 | Overall BRCAm (n = 24) | BRCAw (n = 74) | P | |
---|---|---|---|---|
Germline BRCAm (n = 17) | Only Somatic BRCAm (n = 7) | |||
Age | 53 (42–74) | 54 (48–77) | 56 (22–78) | 0.353 |
Stage | ||||
 I | 0 | 0 | 1 (1.4) | 0.838 |
 II | 1 (5.9) | 0 | 3 (4.1) |  |
 III | 7 (41.2) | 3 (42.9) | 35 (47.3) |  |
 IV | 9 (52.9) | 4 (57.1) | 35 (47.3) |  |
Breast cancer | 2 (11.8) | 0 | 1 (1.4) | 0.084 |
BRCA-related FHx | 4 (23.5) | 3 (42.9) | 9 (12.2) | 0.05 |
NGR | 10 (58.8) | 6 (85.7) | 42 (56.8) | 0.39 |
NAC | 10 (58.8) | 4 (57.1) | 32 (43.2) | 0.242 |