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Table 2 Characteristics of patients with LAPA at initial staging and according to the delivered induction regimen (n = 234)

From: Outcomes of patients with initially locally advanced pancreatic adenocarcinoma who did not benefit from resection: a prospective cohort study

 

FOLFIRINOX (n = 168)

Gemcitabine (n = 66)

P-value

Mean age + SD

64 ± 9.55

75 ± 8.76

< 0.01

Performance status score 2–3 (%)

8 (5)

11 (17)

< 0.01

Mean BMI + SD

23.5 ± 3.81

23.5 ± 4.41

ns

Weight loss > 5% body weight * (%)

110 (65)

50 (76)

ns

Diabetes (%)

10 (6)

5 (7.5)

ns

Back pain (%)

108 (64)

44 (67)

ns

Serum CA 19–9 level* (IU) (+SD)

3884 ± 13,137

1743 ± 4916

ns

Tumour location (%)

  

ns

 Head

117 (70)

44 (65)

 

 Body

40 (24)

17 (26)

 

 Tail

11 (6)

5 (9)

 

Tumour classification (%)

  

ns

 Borderline

116 (69)

42 (64)

 

 Locally advanced

52 (31)

24 (36)

 

Arterial invasion (%)

68 (40.5)

25 (38)

ns

  1. LAPA locally advanced pancreatic adenocarcinoma, BMI body mass index
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BMC Cancer

ISSN: 1471-2407

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