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Table 3 Up-and Down-regulated miRNAs in serum of NPC patients from EG to CG before and after CCRT

From: Serum miRNAs, a potential prognosis marker of loco-regionally advanced nasopharyngeal carcinoma patients treated with CCRT

 

Name

FoldChange (average)

t-test

p-value

Name

FoldChange (average)

t-test

p-value

Before concurrent chemoradiotherapy

After concurrent chemoradiotherapy

Down-regulated miRNAs

miR-29a

0.052

0.0021

miR-29b

0.041

0.009

miR-26b

0.052

0.0275

miR-143

0.013

0.001

 

miR-22

0.068

0.0038

miR-26b

0.013

0.001

 

miR-125b

0.089

0.004

miR-22

0.05

0.0003

 

miR-720

0.458

0.0256

miR-30c

0.074

0.030

 

miR-665

0.489

0.0223

let-7c

0.139

8E-05

    

miR-491-3p

0.179

0.049

    

miR-720

0.221

0.011

    

miR-550

0.294

0.046

Up-regulated miRNAs

hsa-miRPlus-E1253*

2.297

0.0303

hsa-miRPlus-E1072*

2.940

0.037

  1. *Unknown function in current miRNA database