Fig. 1
From: Elastin is a key factor of tumor development in colorectal cancer
ELN mRNA expression is increased in colorectal cancer (CRC) patients, and ELN protein is increased in colon cancer epithelial cells. aELN gene expression was analyzed from colon tissues from healthy controls (n = 5) and CRC patients (n = 31) based on a GSE128449 dataset. bELN gene expression was analyzed from colon tissues from tumor and adjacent non-tumor tissues from the same CRC patients (n = 17) according to a GSE110224 dataset. Colon cancer epithelial cells and normal colon epithelial cells were cultured. c ELN protein was assessed in cell lysates after 24 and 48 h incubation by immunoblot, and d fold change of densitometry normalized to β-actin, n = 4. Results are mean ± SEM. *P < 0.05 compared to normal colon epithelial cells