Table 1 Summary of clinicopathological data of the enrolled cases
No. (%) | ||||
|---|---|---|---|---|
Age (yrs) | Ranged 36 ~ 82 | Mean 63.0 ± 9.4 | ||
Sex | Male 76, Female 50 | M:F = 1.52:1 | ||
Location (tumor epicenter) | Original diagnosis | Revised diagnosis | ||
Periampullary duodenum | 3 | (2.4%) | 0 | (0%) |
AOV | 37 | (29.4%) | 34 | (27.0%) |
Pancreatic head | 37 | (29.4%) | 44 | (34.9%) |
Distal CBD | 47 | (37.3%) | 48 | (38.1%) |
Proximal CBD | 2 | (1.6%) | 0 | (0%) |
T stage | Original diagnosis | Revised diagnosis | ||
Tis | 1 | (0.8%) | 1 | (0.8%) |
T1 | 21 | (16.7%) | 21 | (16.7%) |
T2 | 29 | (23.0%) | 29 | (23.0%) |
T3 | 67 | (53.2%) | 67 | (53.2%) |
T4 | 8 | (6.3%) | 8 | (6.3%) |
Gross type | ||||
Fungating | 20 | (15.9%) | ||
Infiltrative | 93 | (73.8%) | ||
Ulcerofungating | 3 | (2.4%) | ||
Sessile | 5 | (4.0%) | ||
Solid | 2 | (1.6%) | ||
Tumor size | Ranged 0.6 ~ 8.0 cm | Mean 3.2 ± 1.6 cm | ||
< 4.5 cm | 96 | (76.2%) | ||
≥ 4.5 cm | 30 | (23.8%) | ||
N stage | ||||
N0 | 73 | (57.9%) | ||
N1 | 53 | (42.1%) | ||
N2 | 0 | (0%) | ||
M stage | ||||
M0 | 117 | (93.7%) | ||
M1 | 8 | (6.3%) | ||
Absent | Present | |||
Lymphatic invasion | 70 | (55.6%) | 56 | (44.4%) |
Vascular invasion | 110 | (87.3%) | 16 | (12.7%) |
Perineural invasion | 54 | (42.9%) | 72 | (57.1%) |
Positive radial resected margin | 118 | (93.7%) | 8 | (6.3%) |
Tumor ulceration | 116 | (92.1%) | 10 | (7.9%) |
Histologic grade | Original diagnosis | Revised diagnosis | ||
Well differentiated | 37 | (29.4%) | 32 | (25.4%) |
Moderately differentiated | 79 | (62.7%) | 90 | (71.4%) |
Poorly differentiated | 10 | (7.9%) | 4 | (3.2%) |
Histologic subtype | ||||
Pancreaticobiliary subtype | 34 | (27.2%) | ||
Prone to pancreaticobiliary subtype | 58 | (46.4%) | ||
Prone to intestinal subtype | 19 | (15.2%) | ||
Intestinal subtype | 14 | (11.2%) | ||
Degree of fibrosis | Original diagnosis | Revised diagnosis | ||
Absent | 4 | (3.2%) | 1 | (0.8%) |
Mild | 20 | (15.9%) | 35 | (27.8%) |
Moderate | 72 | (57.1%) | 57 | (45.2%) |
Severe | 30 | (23.8%) | 33 | (26.2%) |
Degree of inflammation | Original diagnosis | Revised diagnosis | ||
Mild | 53 | (42.1%) | 42 | (33.3%) |
Moderate | 62 | (49.2%) | 70 | (55.6%) |
Severe | 11 | (8.7%) | 14 | (11.1%) |
Tumor recurrence | Absent | Present | ||
64 | (51.2%) | 61 | (48.8%) | |
Death | 39 | (31.0%) | 87 | (69.0%) |
Follow-up duration (days) | Ranged 3 ~ 5234 | 969.7 ± 1135 | ||
Disease free survival (days) | Ranged 3 ~ 4173 | 731.2 ± 954.5 | ||