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Fig. 2 | BMC Cancer

Fig. 2

From: Accuracy of detecting residual disease after neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma (preSINO trial): a prospective multicenter diagnostic cohort study

Fig. 2

Bite-on-bite biopsy. During bite-on-bite biopsy [1,2,3,4] an extra biopsy [3, 4] is taken at the location of the previous biopsy [1, 2]. This procedure hypothetically increases the chance of detecting residual submucosal disease compared to conventional biopsies [1, 2]. (from: Noordman BJ, Wijnhoven BPL, Lagarde SM, Biermann K, van der Gaast A, Spaander MCW, et al. Active surveillance in clinically complete responders after neoadjuvant chemoradiotherapy for esophageal or junctional cancer. Dis Esophagus. 2017;30 [9]:1–8. With permission of Oxford University Press)

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BMC Cancer

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