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Table 3 Multivariate analysis of various factors correlated with progression-free survival

From: The institutional learning curve is associated with survival outcomes of robotic radical hysterectomy for early-stage cervical cancer-a retrospective study

 

No. of patients

PFS

Multivariate analysis

HR (95% CI)

P

Age, years (continuous)

168

1.025 (0.956–1.099)

0.4894

LC

 2006~2012

77

1 (Reference)

 

 2013~2018

91

0.065 (0.007–0.603)

0.0162*

BMI

 < 25

130

1 (Reference)

 

 ≥ 25

38

0.243 (0.025–2.404)

0.2264

Stage

 IB1, IB2

141

1 (Reference)

 

 IA1, IA2

27

0.638 (0.092–4.446)

0.6502

Histology

 SCC

118

1 (Reference)

 

 AC & AS

50

1.367 (0.375–4.986)

0.6357

Invasiveness

 < 0.3 cm

97

1 (Reference)

 

 ≥ 0.3 cm

71

1.139 (0.297–4.363)

0.8493

LVSI

 No

128

1 (Reference)

 

 Yes

40

4.590 (0.973–21.659)

0.0543

No. of harvested LNs

 < 20

129

1 (Reference)

 

 ≥ 20

39

0.325 (0.068–1.557)

0.1597

Metastatic LNs

 No

155

1 (Reference)

 

 Yes

13

2.609 (0.424–16.041)

0.3006

Tumor size

 < 2 cm

125

1 (Reference)

 

 ≥ 2 cm

43

5.651 (1.255–25.448)

0.0241*

Postoperative treatment

 Yes

34

1 (Reference)

0.0755

 No

134

0.185 (0.029–1.189)

 
  1. PFS Progression-free survival, HR Hazard ratio, CI Confidential interval, LC Learning curve, BMI Body mass index, SCC Squamous cell carcinoma, AC Adenocarcinoma, AS Adenosquamous, LVSI Lymphovascular space invasion, LN Lymph node; *, P < 0.05
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