Table 2 Univariate and multivariable Cox regression analyses of factors associated with overall survival in glioma patients
From: Tumor mutational burden is associated with poor outcomes in diffuse glioma
Variable | Univariate analysis | Multivariable analysis | ||
|---|---|---|---|---|
HR (95% CI) | P* | HR (95% CI) | P | |
Age | 1.86(1.19 to 2.90) | < 0.01 | / | / |
Gender | 1.31(0.87 to 1.98) | 0.19 | / | / |
Grade | 2.61(1.95 to 3.49) | < 0.01 | 2.08(1.53 to 2.82) | < 0.01 |
Histology | 1.45(1.12 to 1.86) | < 0.01 | / | / |
IDH.status | 0.36(0.24 to 0.54) | < 0.01 | / | / |
Chr.1p/19q.codeletion | 0.12(0.05 to 0.27) | < 0.01 | 0.15(0.06 to 0.36) | < 0.01 |
TMB group | 2.58(1.67 to 3.97) | < 0.01 | 1.90(1.21 to 2.98) | < 0.01 |