Fig. 2
From: Tumor mutational burden is associated with poor outcomes in diffuse glioma
TMB is associated with worse outcomes in glioma patients. a Venn diagram of the patients included in further analysis. b ROC analysis of 2-, 3-, and 5-year survival according to TMB. c Kaplan–Meier curves of the overall survival of glioma patients (n = 649, 5 patients lacked survival information) with high TMB (TMBHigh) versus those with low TMB (TMBLow). The cut-off value of the left panel was between 0.64 and 0.67. The right panel had the highest 20%. d-g Survival analysis was performed in the indicated subgroups. h Heatmap showing the distribution of clinical features and genetic characteristics of the glioma specimens (n = 654)