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Table 4 Univariate and multivariate COX regression analysis of prognostic factors in lung cancer patients for PFS

From: Syntenin overexpression in human lung cancer tissue and serum is associated with poor prognosis

Variable

Univariate analysis

Multivariate analysis

Hazard ratio

95%CI

P

Hazard ratio

95%CI

P

Tumor size

1.557

1.130~2.144

0.007

1.162

0.830~1.627

0.383

Distant metastasis

5.754

3.888~8.515

< 0.001

2.773

1.816~4.236

< 0.001

Lymph node metastasis

2.155

1.575~2.950

< 0.001

1.613

1.165~2.234

0.004

Sugical treatment

0.245

0.169~0.353

< 0.001

0.338

0.219~0.522

< 0.001

Age

1.034

0.762~1.402

0.831

   

Sex

0.767

0.540~1.091

0.140

   

Syntenin expression

1.689

1.245~2.291

0.001

1.889

1.369~2.607

< 0.001

Performance status

7.578

4.778~12.020

< 0.001

4.309

2.603~7.131

< 0.001

Histology

0.640

0.395~1.035

0.069

   
  1. Distant metastasis (P < 0.001), lymph node metastasis (P = 0.001), syntenin expression