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Table 3 Univariate and multivariate COX regression analysis of prognostic factors in lung cancer patients for OS

From: Syntenin overexpression in human lung cancer tissue and serum is associated with poor prognosis

Variable

Univariate analysis

Multivariate analysis

Hazard ratio

95%CI

P

Hazard ratio

95%CI

P

Tumor size

1.524

1.104~2.103

0.01

1.319

0.932~1.867

0.118

Distant metastases

4.786

3.331~6.877

< 0.001

2.893

1.916~4.370

< 0.001

Lymph node metastasis

2.102

1.537~2.877

< 0.001

1.604

1.156~2.227

0.005

Sugical treatment

0.274

0.193~0.390

< 0.001

0.489

0.320~0.749

0.001

Age

1.063

0.782~1.445

0.698

   

Sex

0.796

0.559~1.135

0.207

   

Syntenin expression

1.572

1.157~2.136

0.004

1.580

1.141~2.188

0.006

Performance status

8.903

5.700~13.907

< 0.001

6.371

3.750~10.822

< 0.001

Histology

0.595

0.367~0.964

0.035

0.600

0.362~0.994

0.047