Asbestos exposure groups | Cases | Controls | Minimal a | Full b | ||
---|---|---|---|---|---|---|
N | % | N | % | OR (95% CI) | OR (95% CI) | |
Ever exposed to asbestos | ||||||
Never | 538 | 26.7 | 1209 | 59.9 | 1.00 | 1.00 |
Ever | 120 | 6.0 | 151 | 7.5 | 1.58 (1.20–2.08) | 1.32 (0.98–1.77) |
≥ 20 years ago | 44 | 36 | 2.51 (1.57–4.03) | 2.04 (1.25–3.34) | ||
≥ 40 years ago | 84 | 105 | 1.64 (1.19–2.25) | 1.26 (0.90–1.78) | ||
Highest attained concentration of exposure to asbestos | ||||||
Unexposed | 538 | 26.7 | 1209 | 59.9 | 1.00 | 1.00 |
Low | 106 | 5.3 | 134 | 6.6 | 1.55 (1.17–2.07) | 1.29 (0.95–1.76) |
Medium/ High | 14 | 0.7 | 17 | 0.8 | 1.80 (0.85–3.81) | 1.56 (0.73–3.32) |
p-trend | < 0.001 | 0.07 | ||||
Highest attained frequency of exposure to asbestos | ||||||
Unexposed | 538 | 26.7 | 1209 | 59.9 | 1.00 | 1.00 |
< 5% | 4 | 0.2 | 10 | 0.5 | 0.79 (0.24–2.63) | 0.63 (0.18–2.15) |
5–30% | 107 | 5.3 | 122 | 6.1 | 1.75 (1.31–2.35) | 1.45 (1.06–1.98) |
≥ 30% | 9 | 0.5 | 19 | 0.9 | 0.92 (0.40–2.10) | 0.90 (0.39–2.08) |
p-trend | < 0.001 | 0.08 | ||||
Duration of exposure to asbestos (years) | ||||||
Unexposed | 538 | 26.7 | 1209 | 59.9 | 1.00 | 1.00 |
< 9 | 45 | 2.2 | 46 | 2.3 | 1.90 (1.22–2.95) | 1.69 (1.08–2.66) |
9 - < 25 | 39 | 1.9 | 51 | 2.5 | 1.57 (0.99–2.47) | 1.26 (0.78–2.02) |
≥ 25 | 33 | 1.6 | 51 | 2.5 | 1.27 (0.79–2.03) | 1.04 (0.64–1.69) |
Unknown | 3 | 0.2 | 3 | 0.2 | ||
p-trend | < 0.001 | 0.07 | ||||
Duration of exposure at low concentrations of asbestos (years) | ||||||
Unexposed | 547 | 27.1 | 1221 | 60.5 | 1.00 | 1.00 |
< 10 | 44 | 2.2 | 43 | 2.1 | 1.98 (1.26–3.11) | 1.75 (1.10–2.77) |
10 - < 24 | 33 | 1.6 | 44 | 2.2 | 1.43 (0.88–2.33) | 1.13 (0.68–1.87) |
≥ 24 | 31 | 1.5 | 49 | 2.4 | 1.30 (0.80–2.10) | 1.05 (0.63–1.73) |
Unknown | 3 | 0.2 | 3 | 0.2 | ||
p-trend | < 0.001 | 0.11 | ||||
Duration of exposure at medium/high concentrations of asbestos (years) | ||||||
Unexposed | 644 | 31.9 | 1343 | 66.6 | 1.00 | 1.00 |
< 7 | 5 | 0.3 | 8 | 0.4 | 1.61 (0.50–5.19) | 1.39 (0.43–4.46) |
≥ 7 | 9 | 0.5 | 9 | 0.5 | 1.75 (0.66–4.64) | 1.54 (0.58–4.14) |
p-trend | 0.14 | 0.36 | ||||
Cumulative exposure to asbestos | ||||||
Unexposed | 538 | 26.7 | 1209 | 59.9 | 1.00 | 1.00 |
Lowest tertile | 45 | 2.2 | 47 | 2.3 | 1.92 (1.24–2.99) | 1.69 (1.07–2.65) |
Middle tertile | 37 | 1.8 | 48 | 2.4 | 1.47 (0.93–2.34) | 1.22 (0.76–1.97) |
Highest tertile | 35 | 1.7 | 53 | 2.6 | 1.35 (0.85–2.14) | 1.13 (0.70–1.82) |
Unknown | 3 | 0.2 | 3 | 0.2 | 0.01 | 0.23 |
p-trend |