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Table 4 Associations between lymphocyte subsets and clinicopathological parameters

From: Clinical significance of peripheral blood and tumor tissue lymphocyte subsets in cervical cancer patients

 Age (years)FIGO stageHistologyTumor sizeStromal invasionLN metastasisLVSI
≤47> 47PIIIPSCCADCP≤4 cm> 4 cmP≤1/2> 1/2PNoYesPNoYesP
Blood (n = 43)
 Gran %CD453.47 ± 6.062.45 ± 4.080.5372.17 ± 3.924.06 ± 6.490.2662.68 ± 4.955.82 ± 7.500.2162.43 ± 3.393.83 ± 7.030.4312.34 ± 4.883.35 ± 5.510.571.76 ± 2.764.84 ± 7.250.1012.01 ± 3.944.13 ± 6.330.198
 T %MNC57.57 ± 12.2657.19 ± 13.850.92556.69 ± 12.6958.25 ± 13.190.69457.70 ± 13.3955.22 ± 7.180.68853.35 ± 10.2262.55 ± 14.080.01756.56 ± 14.1757.78 ± 12.380.77756.88 ± 13.8258.16 ± 11.550.75156.44 ± 13.5958.44 ± 12.140.614
 CD4%T57.49 ± 9.6553.42 ± 15.930.30457.17 ± 11.7454.19 ± 13.760.44755.41 ± 13.0059.43 ± 9.070.55258.25 ± 10.1652.67 ± 14.940.15359.35 ± 10.6554.24 ± 13.300.22958.17 ± 10.0852.47 ± 15.230.14756.98 ± 10.7254.54 ± 14.570.534
 CD8%T31.18 ± 7.9831.94 ± 13.810.82129.73 ± 9.4833.54 ± 11.790.24831.95 ± 10.9227.10 ± 7.150.39229.64 ± 8.3233.86 ± 12.890.20130.75 ± 9.1931.83 ± 11.370.76429.36 ± 7.7134.48 ± 13.440.12130.70 ± 8.1832.34 ± 12.920.619
 CD4:CD82.06 ± 0.922.03 ± 1.040.9362.22 ± 1.051.85 ± 0.830.2042.02 ± 0.972.35 ± 0.870.5132.20 ± 0.941.85 ± 0.970.2422.22 ± 1.091.97 ± 0.910.442.19 ± 0.891.85 ± 1.040.2542.07 ± 0.922.02 ± 1.020.873
 rdT %T7.2 ± 4.697.45 ± 4.320.916.10 ± 3.708.90 ± 5.060.167.42 ± 4.726.60 ± 2.750.7757.23 ± 4.357.46 ± 4.990.9155.07 ± 3.498.42 ± 4.550.1057.43 ± 4.077.00 ± 5.710.8486.67 ± 4.338.57 ± 4.730.369
 B %MNC6.05 ± 3.076.03 ± 3.250.9836.13 ± 3.505.96 ± 2.710.865.99 ± 3.146.44 ± 3.180.7666.30 ± 3.245.71 ± 2.990.5466.40 ± 3.105.90 ± 3.160.6466.61 ± 3.485.22 ± 2.320.1577.03 ± 3.425.06 ± 2.470.039
 pDC % MNC0.26 ± 0.130.23 ± 0.110.4150.26 ± 0.140.24 ± 0.110.5830.25 ± 0.130.24 ± 0.050.9040.23 ± 0.110.27 ± 0.140.2120.25 ± 0.160.24 ± 0.110.8050.24 ± 0.120.26 ± 0.140.5260.22 ± 0.120.28 ± 0.130.133
 CD11c + % pDC7.71 ± 6.147.49 ± 2.980.9098.09 ± 6.317.01 ± 2.760.5537.40 ± 4.949.13 ± 6.240.5316.74 ± 3.288.91 ± 6.800.2379.31 ± 8.326.96 ± 2.980.4297.83 ± 3.637.27 ± 6.950.7659.24 ± 6.285.78 ± 2.050.044
 Baso % MNC1.09 ± 0.800.83 ± 0.540.2481.07 ± 0730.89 ± 0.690.410.92 ± 0.651.60 ± 1.000.0651.02 ± 0.650.93 ± 0.780.6861.08 ± 0.590.94 ± 0.760.5341.00 ± 0.700.95 ± 0.730.8081.03 ± 0.580.93 ± 0.830.637
 BDCA1+ mDC % MNC0.39 ± 0.180.35 ± 0.190.5470.34 ± 0.230.42 ± 0.100.210.36 ± 0.180.57 ± 0.120.0620.38 ± 0.140.37 ± 0.240.8260.29 ± 0.200.41 ± 0.170.0870.37 ± 0.220.39 ± 0.120.7170.32 ± 0.210.44 ± 0.140.074
 BDCA3+ mDC % MNC0.02 ± 0.040.02 ± 0.040.8750.02 ± 0.040.01 ± 0.030.2370.01 ± 0.040.05 ± 0.070.2030.03 ± 0.0500.020.03 ± 0.050.01 ± 0.040.4770.02 ± 0.040.02 ± 0.040.8710.02 ± 0.040.01 ± 0.040.754
 Mono %MNC17.19 ± 9.5413.30 ± 8.560.17715.88 ± 9.8315.19 ± 8.750.8115.48 ± 9.6016.14 ± 6.600.88416.14 ± 7.8814.83 ± 10.910.65115.80 ± 11.7515.46 ± 8.160.92513.82 ± 8.7717.97 ± 9.590.14915.61 ± 10.1615.50 ± 8.430.97
 CD14+ Mo % MNC16.31 ± 7.3812.18 ± 5.760.10113.64 ± 7.6915.91 ± 5.990.37114.53 ± 7.1715.38 ± 6.350.82414.37 ± 6.0615.02 ± 8.410.80213.21 ± 10.3115.19 ± 5.380.59713.01 ± 6.8917.33 ± 6.530.0913.81 ± 8.4415.56 ± 4.970.476
 CD16+ Mo % MNC2.68 ± 1.653.65 ± 2.770.2742.82 ± 2.473.39 ± 1.790.4733.14 ± 2.322.60 ± 0.890.6523.57 ± 2.492.35 ± 1.440.092.44 ± 2.233.32 ± 2.170.3322.78 ± 1.953.57 ± 2.540.3292.54 ± 1.803.68 ± 2.470.142
 CD16+ %Mono14.68 ± 6.4321.81 ± 8.060.00917.03 ± 8.4118.29 ± 7.330.66117.75 ± 7.8516.38 ± 8.980.74919.47 ± 7.8314.81 ± 7.320.116.34 ± 7.1618.06 ± 8.220.56717.77 ± 7.217.27 ± 8.720.86516.65 ± 8.2918.63 ± 7.480.485
 NK %MNC14.08 ± 7.8919.08 ± 10.700.08916.16 ± 10.0716.05 ± 8.660.9715.92 ± 9.7917.88 ± 2.540.69619.52 ± 9.5911.56 ± 6.890.00516.06 ± 13.2316.13 ± 7.260.98317.82 ± 11.0813.58 ± 5.300.10615.93 ± 10.9916.30 ± 7.400.9
 CD56hi NK % MNC0.33 ± 0.150.33 ± 0.150.9350.32 ± 0.160.34 ± 0.130.8040.33 ± 0.160.35 ± 0.060.5590.31 ± 0.150.36 ± 0.140.30.34 ± 0.190.32 ± 0.130.7040.35 ± 0.170.29 ± 0.110.2410.34 ± 0.180.31 ± 0.110.596
 CD56lo NK % MNC15.29 ± 8.3720.13 ± 10.910.16617.23 ± 10.9517.29 ± 8.010.98617.22 ± 10.2817.53 ± 2.590.95420.55 ± 9.7212.45 ± 7.430.01718.57 ± 15.1416.75 ± 6.790.73618.58 ± 11.4415.06 ± 5.160.24416.66 ± 11.4217.94 ± 7.420.714
 CD56hi %NK2.73 ± 1.942.28 ± 2.260.5532.83 ± 2.562.18 ± 1.130.3452.63 ± 2.181.98 ± 0.610.5631.72 ± 1.063.75 ± 2.570.0172.97 ± 2.532.38 ± 1.880.4762.77 ± 2.432.18 ± 1.230.4413.06 ± 2.561.96 ± 1.090.121
 MDSC % CD33hi1.45 ± 2.452.44 ± 4.330.4161.49 ± 2.702.31 ± 4.040.5012.00 ± 3.520.83 ± 0.930.5181.46 ± 2.432.42 ± 4.360.4340.70 ± 0.572.30 ± 3.830.2260.75 ± 0.683.68 ± 4.940.0650.67 ± 0.633.19 ± 4.500.05
 DR- %14 + APC0.44 ± 1.040.62 ± 2.130.7610.87 ± 2.010.06 ± 0.090.1070.58 ± 1.650.08 ± 0.150.5540.08 ± 0.151.15 ± 2.330.1250.29 ± 0.790.60 ± 1.770.6170.65 ± 1.890.28 ± 0.690.5250.66 ± 1.900.35 ± 1.050.578
 DR- %16 + APC1.13 ± 1.940.53 ± 0.880.3091.38 ± 1.950.24 ± 0.610.0290.99 ± 1.690.13 ± 0.130.3190.49 ± 0.751.46 ± 2.280.160.60 ± 0.811.00 ± 1.830.5391.08 ± 1.900.56 ± 0.920.3810.94 ± 1.280.82 ± 1.950.835
Tissue (n = 35)
 Gran %CD4511.18 ± 15.739.1 ± 7.950.6438.48 ± 10.2911.93 ± 14.630.42810.71 ± 12.975.40 ± 8.500.4958.54 ± 14.4512.28 ± 10.190.39110.46 ± 16.4510.18 ± 11.440.95611.38 ± 13.348.56 ± 9.840.52613.16 ± 15.696.79 ± 6.580.12
 T %MNC63.97 ± 21.8475.21 ± 8.670.0573.72 ± 11.7964.76 ± 21.530.13968.14 ± 18.3079.50 ± 6.170.29869.46 ± 20.4368.70 ± 14.820.90367.14 ± 23.3269.79 ± 16.010.70771.27 ± 17.2965.87 ± 18.780.38871.22 ± 15.4966.61 ± 20.510.455
 CD4%T43.98 ± 16.0147.32 ± 12.530.50448.31 ± 14.1442.86 ± 14.570.2745.13 ± 14.7949.57 ± 10.770.61749.15 ± 13.3841.19 ± 14.820.10550.23 ± 15.2543.87 ± 14.050.2650.45 ± 11.7638.10 ± 15.250.01139.88 ± 13.9252.19 ± 12.290.01
 CD8%T47.34 ± 15.9243.21 ± 11.740.39742.68 ± 12.4748.06 ± 15.410.26645.68 ± 14.3642.93 ± 13.460.75241.10 ± 13.0450.61 ± 13.980.04538.96 ± 12.7447.70 ± 14.100.11140.08 ± 11.8953.50 ± 13.690.00450.61 ± 13.7139.33 ± 12.360.016
 CD4:CD81.17 ± 0.821.24 ± 0.660.7591.32 ± 0.711.09 ± 0.770.3741.19 ± 0.751.31 ± 0.730.8021.41 ± 0.810.96 ± 0.580.071.55 ± 0.961.08 ± 0.620.0991.44 ± 0.730.85 ± 0.620.0190.92 ± 0.551.54 ± 0.800.01
 rdT %T3.43 ± 1.841.53 ± 1.050.0142.55 ± 1.732.60 ± 1.940.9522.42 ± 1.543.95 ± 4.030.6872.57 ± 1.942.59 ± 1.610.9853.44 ± 2.072.11 ± 1.490.1122.61 ± 1.932.43 ± 1.210.8572.75 ± 1.982.04 ± 0.940.454
 B %MNC4.42 ± 3.375.78 ± 3.410.2524.67 ± 3.505.41 ± 3.380.5345.10 ± 3.324.70 ± 5.070.8514.32 ± 2.906.00 ± 3.850.1574.04 ± 2.675.38 ± 3.590.3394.68 ± 3.005.68 ± 4.040.414.54 ± 2.115.65 ± 4.450.372
 pDC % MNC0.66 ± 0.680.64 ± 0.920.940.71 ± 0.850.59 ± 0.740.650.65 ± 0.780.67 ± 0.980.9670.36 ± 0.320.99 ± 1.020.0280.49 ± 0.490.70 ± 0.870.4870.67 ± 0.950.61 ± 0.460.8370.62 ± 0.690.69 ± 0.900.792
 CD11c + % pDC5.39 ± 5.606.21 ± 3.660.6475.76 ± 3.535.81 ± 5.840.9795.64 ± 4.357.70 ± 10.890.8345.57 ± 5.036.13 ± 4.310.7644.21 ± 4.066.38 ± 4.870.2744.77 ± 3.917.70 ± 5.640.1124.97 ± 3.576.93 ± 5.920.321
 Baso % MNC0.11 ± 0.160.06 ± 0.160.3280.12 ± 0.200.05 ± 0.100.1920.08 ± 0.170.13 ± 0.120.60.06 ± 0.130.11 ± 0.190.3750.11 ± 0.180.08 ± 0.160.5910.10 ± 0.190.07 ± 0.110.6750.08 ± 0.160.09 ± 0.170.953
 BDCA1+ mDC % MNC0.11 ± 0.070.11 ± 0.180.8820.11 ± 0.080.11 ± 0.170.9260.11 ± 0.140.10 ± 0.000.9130.11 ± 0.180.11 ± 0.060.9040.10 ± 0.080.11 ± 0.150.820.15 ± 0.170.06 ± 0.050.0740.07 ± 0.070.17 ± 0.180.057
 BDCA3+ mDC % MNC0.03 ± 0.0800.1360.01 ± 0.030.03 ± 0.080.4510.02 ± 0.0600.6820.03 ± 0.080.01 ± 0.030.3920.04 ± 0.110.01 ± 0.030.4640.03 ± 0.080.01 ± 0.030.3920.01 ± 0.020.03 ± 0.090.317
 Mono %MNC10.22 ± 9.846.28 ± 5.500.1649.48 ± 9.177.41 ± 7.470.4688.78 ± 8.524.50 ± 4.040.45.48 ± 4.7811.90 ± 10.220.0328.90 ± 11.808.25 ± 6.980.8437.42 ± 8.059.91 ± 8.710.39310.33 ± 10.366.15 ± 4.090.119
 CD14+ Mo % MNC2.62 ± 2.761.76 ± 1.770.3292.43 ± 2.721.96 ± 1.920.5932.28 ± 2.391.15 ± 1.200.5191.34 ± 1.313.61 ± 2.980.0342.06 ± 2.862.26 ± 2.180.8452.35 ± 2.381.93 ± 2.360.6562.79 ± 2.781.37 ± 1.180.071
 CD16+ Mo % MNC6.19 ± 7.025.09 ± 4.160.6156.15 ± 5.325.12 ± 6.330.6385.78 ± 5.884.00 ± 4.380.6813.49 ± 2.989.19 ± 7.430.0324.06 ± 6.196.26 ± 5.610.3664.88 ± 6.097.13 ± 4.990.3255.91 ± 7.015.29 ± 3.510.781
 CD16+ %Mono68.75 ± 13.3975.44 ± 12.310.17474.09 ± 13.7469.72 ± 12.480.37971.65 ± 13.5276.50 ± 2.550.62272.47 ± 13.2871.19 ± 13.390.80468.29 ± 14.5173.39 ± 12.610.35867.45 ± 13.0480.59 ± 8.240.00868.74 ± 13.1976.58 ± 12.010.113
 NK %MNC7.45 ± 16.283.58 ± 4.040.3762.39 ± 1.639.10 ± 17.140.1276.00 ± 12.811.60 ± 0.280.6357.69 ± 16.473.28 ± 2.400.3131.83 ± 0.927.15 ± 14.330.2793.86 ± 4.568.78 ± 19.400.2693.92 ± 4.758.06 ± 18.080.343
 CD56hi NK % MNC5.69 ± 15.712.75 ± 3.900.5021.56 ± 1.517.18 ± 16.300.2214.54 ± 11.910.65 ± 0.210.6535.95 ± 14.481.53 ± 1.330.3251.34 ± 0.695.39 ± 13.450.4072.33 ± 3.337.97 ± 19/170.3792.28 ± 3.497.10 ± 17.470.274
 CD56lo NK % MNC1.42 ± 2.550.97 ± .880.5380.87 ± 0.861.56 ± 2.610.3451.23 ± 1.980.90 ± 0.140.8211.23 ± 2.341.15 ± 0.960.9170.44 ± 0.411.50 ± 2.180.1880.98 ± 0.851.63 ± 3.100.3930.98 ± 0.891.52 ± 2.820.469
 CD56hi %NK69.20 ± 19.9663.24 ± 27.930.51259.81 ± 26.3773.30 ± 19.460.12868.18 ± 23.7141.25 ± 2.470.12672.92 ± 22.7255.53 ± 22.660.05577.68 ± 16.9662.00 ± 25.040.06865.42 ± 24.1668.03 ± 24.560.78564.04 ± 24.6869.56 ± 23.290.549
 MDSC % CD33hi2.58 ± 3.272.22 ± 4.340.8031.16 ± 1.923.74 ± 4.770.0762.55 ± 3.860.50 ± 0.710.4672.71 ± 4.151.92 ± 3.150.5941.99 ± 2.982.57 ± 4.070.7182.94 ± 4.481.39 ± 1.470.2993.22 ± 4.661.26 ± 1.390.118
 DR- %14 + APC12.53 ± 18.6523.71 ± 16.820.10219.69 ± 20.9716.04 ± 15.690.60219.25 ± 18.36//14.93 ± 15.8622.83 ± 21.800.26915.24 ± 18.1618.95 ± 18.800.63621.95 ± 19.3310.27 ± 14.270.10523.35 ± 19.7810.23 ± 13.430.057
 DR- %16 + APC1.64 ± 2.561.54 ± 3.350.9312.06 ± 3.671.09 ± 1.830.3821.59 ± 3.001.65 ± 2.190.9781.56 ± 3.051.65 ± 2.830.9312.81 ± 4.281.13 ± 2.170.1692.37 ± 3.370.11 ± 0.160.0092.42 ± 3.540.42 ± 0.950.038