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Table 1 Relationships between the percentage of PD-1+ CD68+ cell and clinicopathological variables

From: Increased PD-1-positive macrophages in the tissue of gastric cancer are closely associated with poor prognosis in gastric cancer patients

 

PD-1+ macrophage (%)

P value

Gender

 

0.24

 Male (n = 75)

2.40 (±4.15)

 

 Female (n = 27)

1.24 (±2.45)

 

Age

 

0.036

 ≥ 75 (n = 36)

3.31 (±4.93)

 

 < 75 (n = 66)

1.42 (±2.83)

 

Depth of invasion a

 

0.86

 T1 (n = 12)

3.04 (±5.18)

 

 T2–4 (n = 90)

1.96 (±3.60)

 

Lymph node metastasis

 

< 0.001

 Absent (n = 54)

0.54 (±1.19)

 

 Present (n = 48)

3.83(±4.86)

 

Tumor size

 

0.14

 ≥ 4 cm (n = 60)

2.48 (±3.97)

 

 < 4 cm (n = 42)

1.53 (±3.51)

 

Histology b

 

0.47

 Differentiated (n = 54)

2.22 (±3.93)

 

 Undifferentiated (n = 48)

1.95 (±3.68)

 

Lymphatic invasion

 

0.063

 Absent (n = 12)

0.47 (±1.20)

 

 Present (n = 90)

2.30 (±3.97)

 

Venous invasion

 

0.089

 Absent (n = 17)

0.93 (±2.11)

 

 Present (n = 85)

2.32 (±4.02)

 
  1. All results expressed as mean ± SD
  2. aDepth of invasion: T1: tumor has invaded lamina propria or submucosa; T2: tumor has invaded the muscularis propria; T3: tumor has invaded the subserosa; T4: tumor invasion is contiguous to, or exposed beyond, the serosa or has invaded adjacent structures
  3. bDifferentiated, papillary, or tubular adenocarcinoma; undifferentiated, poorly differentiated, mucinous adenocarcinoma, and signet-ring cell carcinoma