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Table 7 Mean difference of performance status scores

From: Efficacy and safety of bupropion in cancer-related fatigue, a randomized double blind placebo controlled clinical trial

(A)

(B)

 

Mean difference (A-B)

SE

95% Confidence interval of difference

P-value

Lower

Upper

Baseline (ECOG)

End of 2nd week (ECOG)

Placebo

0

0

0

0

0

Bupropion

0.15

0.1

- 0.07

0.38

0.16

End of 6th week (ECOG)

Placebo

0.14

0.09

- 0.06

0.3

0.16

Bupropion

0.8

0.1

0.6

1.07

0.001>

End of 2nd week (ECOG)

End of 6th week (ECOG)

Placebo

0.14

0.09

- 0.067

0.3

0.16

Bupropion

0.7

0.13

0.4

0.98

0.001>

Baseline (Karnofsky)

End of 2nd week (Karnofsky)

Placebo

0

0

0

0

–

Bupropion

- 2.3

1.2

- 4.9

0.3

0.08

End of 6th week (Karnofsky)

Placebo

- 2.8

1.6

- 6.38

0.67

0.1

Bupropion

- 12.3

1.2

- 14.9

- 9.6

0.001>

End of 2nd week (Karnofsky)

End of 6th week (Karnofsky)

Placebo

- 2.8

1.6

- 6.38

0.67

0.1

Bupropion

- 10

1.1

- 12.4

- 7.5

0.001>