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Table 2 Mean scores of BFI and FACIT in cancer patients during the study

From: Efficacy and safety of bupropion in cancer-related fatigue, a randomized double blind placebo controlled clinical trial

(A)

(B)

 

Mean difference (A-B)

SE

95% Confidence interval of difference

P-value

Lower

Upper

Baseline (BFI)

End of 2nd week (BFI)

Placebo

0.16

0.06

0.03

0.3

0.017

Bupropion

0.64

0.16

0.27

1

0.002

End of 6th week (BFI)

Placebo

0.49

0.1

0.27

0.7

0.001>

Bupropion

1.8

0.17

1.8

2.2

0.001>

End of 2nd week (BFI)

End of 6th week (BFI)

Placebo

0.3

0.11

0.08

0.56

0.01

Bupropion

1.16

0.14

0.8

1.4

0.001>

Baseline (FACIT)

End of 2nd week (FACIT)

Placebo

- 0.57

0.7

- 2.1

0.9

0.4

Bupropion

- 3.15

0.67

- 6.4

- 1.67

0.001

End of 6th week (FACIT)

Placebo

- 1.8

1

- 4

0.3

0.09

Bupropion

- 7

0.9

- 9

- 5

0.001>

End of 2nd week (FACIT)

End of 6th week (FACIT)

Placebo

- 1.28

1.2

- 4

1.4

0.2

Bupropion

- 3.9

0.5

- 5

- 2.7

0.001>