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Table 3 Multivariate Analyses of OS and BCSM in original samples and matched samples

From: Adjuvant chemotherapy could not bring survival benefit to HR-positive, HER2-negative, pT1b-c/N0–1/M0 invasive lobular carcinoma of the breast: a propensity score matching study based on SEER database

Variable

original samples

matched samples

 

HR for

95%CI

P

HR for

95%CI

P

HR for

95%CI

P

HR for

95%CI

P

OS

BCSM

OS

BCSM

Age (years)

< 40

Reference

  

Reference

  

Reference

  

Reference

  

40–49

0.95

0.22–4.08

0.949

0.66

0.14–3.01

0.597

0.84

0.19–3.70

0.814

0.86

0.19–3.96

0.857

50–59

0.55

0.14–2.27

0.410

1.04

0.24–4.39

0.957

0.49

0.12–2.06

0.333

1.07

0.24–4.65

0.923

60–69

0.36

0.09–1.44

0.147

0.83

0.19–3.53

0.805

0.29

0.07–1.20

0.087

0.91

0.20–4.05

0.903

70–79

0.16

0.04–0.63

0.009

2.24

0.53–9.39

0.268

0.19

0.05–0.81

0.025

1.43

0.30–6.82

0.650

Race

Black

Reference

  

Reference

  

Reference

  

Reference

  

White

1.61

1.21–2.15

0.001

0.61

0.36–1.04

0.075

2.32

1.50–3.60

0.001

0.39

0.20–0.75

0.005

Others

1.64

1.01–2.68

0.047

0.54

0.21–1.40

0.211

2.54

1.10–5.90

0.030

0.25

0.05–1.12

0.071

Tumor

(Ic vs Ib)

0.84

0.67–1.04

0.111

1.39

0.88–2.20

0.153

0.87

0.56–1.34

0.524

1.50

0.70–3.22

0.290

LN

(N1 vs N0)

0.61

0.48–0.78

0.001

2.11

1.37–3.24

0.001

0.76

0.54–1.07

0.112

1.66

0.96–2.88

0.069

Grade

I

Reference

  

Reference

  

Reference

  

Reference

  

II

0.96

0.78–1.18

0.679

1.35

0.88–2.07

0.158

0.84

0.56–1.25

0.384

1.38

0.71–2.66

0.332

III

0.85

0.57–1.26

0.418

1.69

0.84–3.42

0.141

0.66

0.37–1.17

0.156

1.35

0.50–3.64

0.552

Surgery

No surgery

Reference

  

Reference

  

Reference

  

Reference

  

BCS

7.19

4.91–10.53

0.001

0.06

0.03–0.12

0.001

10.84

5.39–21.80

0.001

0.06

0.02–0.17

0.001

Mastectomy

7.39

5.24–10.41

0.001

0.06

0.03–0.10

0.001

8.11

4.51–14.58

0.001

0.08

0.03–0.19

0.001

Chemotherapy

(Yes vs No)

0.82

0.62–1.09

0.172

2.33

1.47–3.67

0.001

0.90

0.65–1.26

0.553

2.41

1.32–4.39

0.004

Radiotherapy

(Yes vs No)

2.07

1.58–2.70

0.001

0.48

0.29–0.82

0.007

1.41

0.89–2.23

0.142

0.66

0.32–1.34

0.253