Variable | original samples | matched samples | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR for | 95%CI | P | HR for | 95%CI | P | HR for | 95%CI | P | HR for | 95%CI | P | ||
OS | BCSM | OS | BCSM | ||||||||||
Age (years) | < 40 | Reference | Reference | Reference | Reference | ||||||||
40–49 | 0.95 | 0.22–4.08 | 0.949 | 0.66 | 0.14–3.01 | 0.597 | 0.84 | 0.19–3.70 | 0.814 | 0.86 | 0.19–3.96 | 0.857 | |
50–59 | 0.55 | 0.14–2.27 | 0.410 | 1.04 | 0.24–4.39 | 0.957 | 0.49 | 0.12–2.06 | 0.333 | 1.07 | 0.24–4.65 | 0.923 | |
60–69 | 0.36 | 0.09–1.44 | 0.147 | 0.83 | 0.19–3.53 | 0.805 | 0.29 | 0.07–1.20 | 0.087 | 0.91 | 0.20–4.05 | 0.903 | |
70–79 | 0.16 | 0.04–0.63 | 0.009 | 2.24 | 0.53–9.39 | 0.268 | 0.19 | 0.05–0.81 | 0.025 | 1.43 | 0.30–6.82 | 0.650 | |
Race | Black | Reference | Reference | Reference | Reference | ||||||||
White | 1.61 | 1.21–2.15 | 0.001 | 0.61 | 0.36–1.04 | 0.075 | 2.32 | 1.50–3.60 | 0.001 | 0.39 | 0.20–0.75 | 0.005 | |
Others | 1.64 | 1.01–2.68 | 0.047 | 0.54 | 0.21–1.40 | 0.211 | 2.54 | 1.10–5.90 | 0.030 | 0.25 | 0.05–1.12 | 0.071 | |
Tumor | (Ic vs Ib) | 0.84 | 0.67–1.04 | 0.111 | 1.39 | 0.88–2.20 | 0.153 | 0.87 | 0.56–1.34 | 0.524 | 1.50 | 0.70–3.22 | 0.290 |
LN | (N1 vs N0) | 0.61 | 0.48–0.78 | 0.001 | 2.11 | 1.37–3.24 | 0.001 | 0.76 | 0.54–1.07 | 0.112 | 1.66 | 0.96–2.88 | 0.069 |
Grade | I | Reference | Reference | Reference | Reference | ||||||||
II | 0.96 | 0.78–1.18 | 0.679 | 1.35 | 0.88–2.07 | 0.158 | 0.84 | 0.56–1.25 | 0.384 | 1.38 | 0.71–2.66 | 0.332 | |
III | 0.85 | 0.57–1.26 | 0.418 | 1.69 | 0.84–3.42 | 0.141 | 0.66 | 0.37–1.17 | 0.156 | 1.35 | 0.50–3.64 | 0.552 | |
Surgery | No surgery | Reference | Reference | Reference | Reference | ||||||||
BCS | 7.19 | 4.91–10.53 | 0.001 | 0.06 | 0.03–0.12 | 0.001 | 10.84 | 5.39–21.80 | 0.001 | 0.06 | 0.02–0.17 | 0.001 | |
Mastectomy | 7.39 | 5.24–10.41 | 0.001 | 0.06 | 0.03–0.10 | 0.001 | 8.11 | 4.51–14.58 | 0.001 | 0.08 | 0.03–0.19 | 0.001 | |
Chemotherapy | (Yes vs No) | 0.82 | 0.62–1.09 | 0.172 | 2.33 | 1.47–3.67 | 0.001 | 0.90 | 0.65–1.26 | 0.553 | 2.41 | 1.32–4.39 | 0.004 |
Radiotherapy | (Yes vs No) | 2.07 | 1.58–2.70 | 0.001 | 0.48 | 0.29–0.82 | 0.007 | 1.41 | 0.89–2.23 | 0.142 | 0.66 | 0.32–1.34 | 0.253 |