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Table 2 Treatment and patient outcomes

From: Serum levels of soluble programmed death-ligand 1 (sPD-L1) in patients with primary central nervous system diffuse large B-cell lymphoma

 

All patients

(n = 68)

Low sPD-L1

(n = 36)

High sPD-L1

(n = 32)

 
 

n

(%)

n

(%)

n

(%)

P

HD-MTX chemotherapy

 Completed

61

(90)

32

(89)

29

(91)

>  0.999

 Failed to complete

7

(10)

4

(11)

3

(9)

 

Response to HD-MTX treatment

 CR/PR

54/12

(97)

30/6

(100)

24/6

(94)

0.486

 SD/PD

1/1

(3)

0/0

(0)

1/1

(6)

 

Intrathecal chemotherapy

 Combined

26

(38)

10

(28)

16

(50)

0.081

 Not combined

42

(62)

26

(72)

16

(50)

 

Whole brain radiotherapy

 Done

45

(66)

24

(67)

21

(67)

>  0.999

 Not done

23

(34)

12

(33)

11

(34)

 

Relapse after primary treatment

 No relapse

29

(43)

18

(50)

11

(34)

0.226

 Relapse

39

(57)

18

(50)

21

(66)

 

Autologous stem cell transplantation

 Done

12

(18)

7

(19)

5

(16)

0.758

 Not done

56

(82)

29

(81)

27

(84)

 

Relapse or progression

 None

25

(37)

18

(50)

7

(22)

0.023

 Occurred

43

(63)

18

(50)

25

(78)

 

Survival status

 Alive

39

(57)

27

(75)

12

(37)

0.003

 Dead

29

(43)

9

(25)

20

(63)

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