Table 3 Specific RT volume definition volumes for Arm 2 (Primary TOS) if adjuvant RT is required
| Radiotherapy Volume | Definition | |
|---|---|---|
| With ENE or positive margins (30 fractions over 6 weeks) | Without ENE or positive margins (25 fractions over 5 weeks) | |
| CTV60 | Areas of positive margins and/or ENE | |
| CTV54 | CTV50 | Entire tumor bed and any dissected neck nodal levels |
| CTV48 | CTV45 | Undissected nodal areas that must be treated based on pathological results. Treatment volumes must include nodal levels adjacent to areas containing involved nodes (eg. if there is a level II node positive, levels Ib and V must be included) – All patients with N1 (ipsilateral) nodal disease: ◦Ipsilateral: Ib, II-V, RP ◦Contralaterala: II-IV, RP only if extension to posterior pharyngeal wall or soft palate – All patients with N2 disease: ◦Ipsilateral and contralateral: Ib, II-V, RP |