High Risk | A least three family members affected by CRC, or at least two affected by CRC and one affected by endometrial cancer. One relative must be aged ≤50 years and one must be a first degree relative. | Medium Risk | One first degree relative with CRC ≤45 years |
Gene carriers (HNPCC) | Two first degree relatives affected (one aged < 55 years) | ||
Untested first degree relatives of gene carriers | At least two relatives with CRC or endometrial cancer who are first degree relatives of each other |