Fig. 2

Schematic view showing the relation between cfDNA determined in plasma (ng/mL) and cases with ctDNA, totaling 37 plasma samples from 18 patients. cfDNA mutations detected by NGS are depicted in red bars with their corresponding AFs (%).The AF represented in the event of ≥2 mutations per sample is the highest. Samples from the same patient at different timepoints are represented using the patient number followed by a dash and the number of the timepoint. Genotype from cfDNA mutations has been divided accordingly to the type of mutation. Black spots in the KIT/PDGFRA genotype part of the graph represent positive samples for ddPCR. At the bottom, it is displayed an overview of clinical, pathological and molecular characteristics