Table 2 Comparison of clinicopathologic and radiological features between patients with and without LVI
Parameters | No. of patients without LVI (n = 197) | No. of patients with LVI (n = 104) | P value* |
|---|---|---|---|
Age (years) | |||
Mean | 50.0 ± 10.8 | 49.6 ± 11.4 | 0.767 |
Median | 49.0 | 48.0 | – |
< 50 (n = 167) | 105 (62.9) | 62 (37.1) | 0.294 |
≥ 50 (n = 134) | 92 (68.7) | 42 (31.3) | |
Tumor location | |||
Upper-outer quadrant (n = 14 6) | 96 (65.8) | 50 (34.2) | 0.028 |
Lower-outer quadrant (n = 44 ) | 33 (75.0) | 11 (25.0) | |
Upper-inner quadrant (n = 74 ) | 51 (68.9) | 23 (31.1) | |
Lower-inner quadrant (n = 19 ) quadrant (n = 31) | 11 (57.9) | 8 (42.1) | |
Central position (n = 18) | 6 (33.3) | 12 (66.7) | |
Tumor size (mm) | |||
< 30 (n = 176) | 124 (70.5) | 52 (29.5) | 0.030 |
≥ 30 (n = 125) | 73 (58.4) | 52 (41.6) | |
Margins | |||
Well-defined (n = 95) | 82 (86.3) | 13 (13.7) | < 0.001 |
Ill-defined (n = 206) | 115 (55.8) | 91 (44.2) | |
Lobulation sign Hyperechogenicity (n = 61) | |||
Absence (n = 135) | 110 (81.5) | 25 (18.5) | < 0.001 |
Presence (n = 166) | 87 (52.4) | 79 (47.6) | |
Spiculation sign | |||
Absence (n = 122) | 88 (72.1) | 34 (27.9) | 0.044 |
Presence (n = 179) | 109 (60.9) | 70 (39.1) | |
MRI-reported ALNM | |||
Absent (n = 92) | 43 (46.7) | 49 (53.3) | < 0.001 |
Single (n = 51) | 32 (62.7) | 19 (37.3) | |
Multiple (n = 158) | 122 (77.2) | 36 (22.8) | |
DWI appearance | |||
Slight-moderate hyperintensity (n = 113) | 92 (81.4) | 21 (18.6) | < 0.001 |
Marked hyperintensity (n = 188) | 105 (55.9) | 83 (44.1) | |
TIC pattern | |||
Type I (n = 25) | 24 (96.0) | 1 (4.0) | < 0.001 |
Type II (n = 229) | 152 (66.4) | 77 (33.6) | |
Type III (n = 47) | 21 (44.7) | 26 (55.3) | |
ER (%) | |||
< 50 (n = 116) | 72 (62.1) | 44 (37.9) | 0.329 |
≥ 50 (n = 185) | 125 (67.6) | 60 (32.4) | |
PR (%) | |||
< 50 (n = 191) | 120 (62.8) | 71 (37.2) | 0.208 |
≥ 50 (n = 110) | 77 (70.0) | 33 (30.0) | |
HER2 | |||
- (n = 23) | 19 (82.6) | 4 (17.4) | 0.132 |
+ (n = 63) | 45 (71.4) | 18 (28.6) | |
++ (n = 149) | 93 (63.3) | 54 (36.7) | |
+++ (n = 68) | 40 (58.8) | 28 (41.2) | |
Ki-67 (%) index | |||
< 20 (n = 99) | 64 (64.6) | 35 (35.4) | 0.838 |
≥ 20 (n = 202) | 133 (65.8) | 69 (34.2) | |
Histological type | |||
IDC grade 3 (n = 106) | 58 (54.7) | 48 (45.3) | < 0.001 |
IDC grade 2 (n = 149) | 98 (65.8) | 51 (34.2) | |
DCIS (n = 46) | 41 (89.0) | 5 (11.0) | |