Table 1 Clinicopathological characteristics of breast cancer patients and healthy controls
Characteristics | Total Number of patients | Number of patients with Wild type TP53 | Number of patients with mutated TP53 | Number of healthy controls |
|---|---|---|---|---|
Ethnicity | ||||
 Sinhalese | 25 | 18 | 7 | 24 |
 Tamil | 1 | 1 | 0 | 5 |
 Muslims | 2 | 2 | 0 | 0 |
 Burgher | 2 | 0 | 2 | 1 |
Age at study entry | ||||
  < 40 years | 1 | 1 | 0 | 9 |
 40–60 years | 14 | 11 | 3 | 13 |
  > 61 years | 15 | 10 | 5 | 8 |
Body Mass Index | ||||
 Underweight | 2 | 2 | 0 | 2 |
 Ideal | 9 | 7 | 2 | 9 |
 Overweight | 5 | 4 | 1 | 4 |
 Pre obese | 10 | 6 | 4 | 11 |
 Obese | 4 | 2 | 2 | 4 |
Tumour type | ||||
 Invasive Ductal Carcinoma | 29 | 20 | 9 | N/A |
 Invasive Lobular Carcinoma | 1 | 1 | 0 | N/A |
Breast affected | ||||
 Left | 11 | 7 | 4 | N/A |
 Right | 17 | 13 | 4 | N/A |
 both | 2 | 1 | 1 | N/A |
Menstrual status | ||||
 Pre menopausal | 7 | 5 | 2 | 19 |
 Post menopausal | 23 | 16 | 7 | 11 |
Pregnancy history | ||||
 Nulliparous | 7 | 4 | 3 | 9 |
 1–3 children | 21 | 16 | 5 | 20 |
  > 3 children | 2 | 1 | 1 | 1 |
Breast Feeding history (Total) | ||||
 No breast feeding | 7 | 4 | 3 | 9 |
  < = one year | 4 | 3 | 1 | 8 |
  > one year | 18 | 13 | 5 | 13 |
History of cancer | ||||
 Previous history | 6 | 3 | 3 | N/A |
 Family history | 11 | 8 | 3 | N/A |
Codon 72 polymorphism | ||||
 Arginine | 12 | 10 | 2 | 12 |
 Proline | 7 | 2 | 5 | 5 |
 Arginine/ Proline | 11 | 9 | 2 | 13 |