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Fig. 1 | BMC Cancer

Fig. 1

From: Pattern of nucleotide variants of TP53 and their correlation with the expression of p53 and its downstream proteins in a Sri Lankan cohort of breast and colorectal cancer patients

Fig. 1

Novel frameshift deletions detected in exon 8. a Mutation Surveyor®V4.0.9 images indicating the heterozygous deletion point; R indicates the reference TP53 sequence and S indicates the study sample TP53 sequence. (i. - c.848_849delGC, ii - c.851_855delCAGAG). b Protein prediction using Mutalyzer 2.0.26. (i. - c.848_849delGC, ii - c.851_855delCAGAG). c Superimposed image of predicted mutated protein with wildtype p53 protein (PDB ID – 1TUP) Red indicates the mutated protein, Blue indicates the wildtype protein (i. - c.848_849delGC, ii - c.851_855delCAGAG)

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