The effect of renal function change on renal cell carcinoma patients with tumor thrombus after nephrectomy and thrombectomy: a large Chinese center experience

Table 3 Linear regression analysis of percent change in eGFR

Variables	Univariate analysis			Multivariate analysis
Variables	B	95%CI	P	B	95%CI	P
Gender (female vs. male)	0.047	−0.289-0.383	0.782
Age	− 0.009	− 0.023-0.004	0.182
Body mass index	0.028	−0.013-0.069	0.182
ASA classification	−0.107	−0.426-0.212	0.507
Side (right vs. left)	−0.167	−0.469-0.135	0.276
Tumor diameter	0.044	0.003–0.085	0.037^*	0.037	−0.001-0.074	0.058
Tumor thrombus grade	0.016	−0.106-0.138	0.794
Preoperative serum creatinine	0.01	0.009–0.011	< 0.001^*	–	–	–
Preoperative eGFR	−0.014	−0.020--0.007	< 0.001^*	−0.013	− 0.019--0.007	< 0.001^*
Operation approach (open vs. laparoscopy)	−0.101	− 0.394-0.192	0.496
Operation time	0.001	0.000–0.002	0.094
Pathological type (non-clear cell carcinoma vs. clear cell carcinoma)	0.59	0.191–0.988	0.004^*	0.623	0.236–1.010	0.002^*
Vascular wall invasion (present vs. absent)	0.247	−0.049-0.543	0.101
Lymphatic vascular invasion (present vs. absent)	−0.128	−0.485-0.229	0.48
Perinephric tissues invasion (present vs. absent)	0.156	−0.163-0.475	0.336
Renal pelvis invasion (present vs. absent)	0.368	0.020–0.716	0.038^*
Necrosis (present vs. absent)	−0.16	−0.455-0.134	0.284
Sarcomatoid differentiation (present vs. absent)	−0.066	−0.464-0.332	0.743

eGFR estimated glomerular filtration rate, ISUP International Society of Urological Pathology, ASA American Society of Anesthesiologists; *p<0.05

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