From: Increased plasma concentration of cell-free DNA precedes disease recurrence in children with high-risk neuroblastoma
Time point of recurrence
Total cases (n = 36)
with 13-cis-retinoic acid
31
the first-three months
5
next 6–9 months
26
after 13-cis-retinoic acid stopped
3–6 months
2
6–12 months
Over 12 months
1