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Table 2 Recurrence disease of NB during maintenance treatment

From: Increased plasma concentration of cell-free DNA precedes disease recurrence in children with high-risk neuroblastoma

Time point of recurrence

Total cases (n = 36)

with 13-cis-retinoic acid

31

the first-three months

5

next 6–9 months

26

after 13-cis-retinoic acid stopped

5

3–6 months

2

6–12 months

2

Over 12 months

1