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Table 1 Characteristics of NB patients with high risk

From: Increased plasma concentration of cell-free DNA precedes disease recurrence in children with high-risk neuroblastoma

Characteristics

Total cases, N (%)

Age (months)

 < 18

7 (6.0)

 ≥ 18 and < 60

80 (69.0)

 ≥ 60

29 (25.0)

Sex

 Female

56 (48.3)

 Male

60 (51.7)

Primary site

 Abdomen

93 (80.2)

 Thorax

20 (17.2)

 Other

3 (2.6)

MYCN gene

 Amplification

38 (32.8)

 Non-amplification

78 (67.2)

NSE (ng/ml)

 < 370

88 (75.9)

 ≥ 370

28 (24.1)

LDH (IU/L)

 ≤ 500

14 (12.1)

 > 500 and < 1500

88 (75.9)

 ≥ 1500

14 (12.1)

Metastatic site

 Bone

84 (72.4)

 Bone marrow

72 (62.1)

 Distant lymph node

76 (65.5)

 Liver

20 (17.2)

 Central nervous system

20 (17.2)

Number of organs with metastasis

 < 3

59 (50.9)

 3

39 (33.6)

 > 3

18 (15.5)