III | IVA-IVB | |||||||
---|---|---|---|---|---|---|---|---|
Characteristic | TPF(n = 320) No. (%) | PF(n = 167) No. (%) | TP(n = 125) No. (%) | P | TPF(n = 452) No. (%) | PF(n = 173) No. (%) | TP(n = 117) No. (%) | P |
Age, y | 0.106a | 0.865a | ||||||
Median (range) | 42(13–70) | 44(18–68) | 46 (19–64) | 45(8–74) | 45(15–71) | 46 (18–71) | ||
< 45 | 186(58.1) | 89(53.3) | 59(47.2) | 225(49.8) | 82(47.4) | 57(48.7) | ||
≥ 45 | 134(41.9) | 78(46.7) | 66(52.8) | 227(50.2) | 91(52.6) | 60(51.3) | ||
Gender | 0.151a | 0.668a | ||||||
Female | 78(24.4) | 53(31.7) | 29(26.1) | 106 (23.5) | 38(22.0) | 31(26.5) | ||
Male | 242(75.6) | 114(68.3) | 96(76.8) | 346(76.5) | 135(78.0) | 86(73.5) | ||
Pathological type | 0.660b | 0.370b | ||||||
WHO type I | 0(0) | 0(0) | 0(0) | 3(0.7) | 1(0.6) | 0(0) | ||
WHO type II | 2(0.6) | 2(1.2) | 0(0) | 2(0.4) | 3(1.7) | 0(0) | ||
WHO type III | 318(99.4) | 165(98.8) | 125(100) | 447(98.9) | 169(97.7) | 117(100) | ||
T stagec | 0.049b | 0.426a | ||||||
T1 | 4(1.3) | 3(1.8) | 1(0.8) | 7(1.5) | 2(1.2) | 1(0.9) | ||
T2 | 41(12.8) | 38(22.8) | 23(18.4) | 30(6.6) | 11(6.4) | 6(5.1) | ||
T3 | 275(85.9) | 126(75.4) | 101(80.8) | 104(48.1) | 168(48.4) | 118(47.6) | ||
T4 | 0 (0) | 0 (0) | 0 (0) | 311(39.5) | 118(34.0) | 93(37.5) | ||
N stagec | < 0.001a | 0.047 a | ||||||
N0 | 6(1.9) | 1(0.6) | 5(4.0) | 9(2.0) | 10(5.8) | 4(3.4) | ||
N1 | 95(29.7) | 17(10.2) | 32(25.6) | 98(21.7) | 40(23.1) | 33(28.2) | ||
N2 | 219(68.4) | 149(89.2) | 88(70.4) | 148(432.7) | 48(27.7) | 43(36.8) | ||
N3 | 0 (0) | 0 (0) | 0 (0) | 197(43.6) | 75(43.4) | 37(31.6) | ||
EBV DNA | 0.085a | 0.007 a | ||||||
≥ 1500 | 188(58.8) | 104(62.3) | 62(49.6) | 326(72.1) | 127(73.4) | 68(58.1) | ||
< 1500 | 132 (41.3) | 63(37.7) | 63(50.4) | 126(27.9) | 46(26.6) | 49(41.9) | ||
RT technique | < 0.001a | < 0.001 b | ||||||
2D RT | 5(1.6) | 52(31.1) | 9(7.2) | 2(0.4) | 49(28.3) | 2(1.7) | ||
IMRT | 315(98.4) | 115(68.9) | 116(92.8) | 450(99.6) | 124(71.7) | 115(98.3) | ||
CCD (mg/m2) | 0.032 a | 0.791 a | ||||||
Median (range) | 160(68–300) | 160(40–250) | 160(60–300) | 160(25–300) | 160(50–240) | 160(20–300) | ||
≥ 200 | 85(26.6) | 27(16.3) | 27(21.6) | 98(21.7) | 36(20.8) | 22(18.8) | ||
< 200 | 235(73.4) | 140(83.8) | 98(78.4) | 354(78.3) | 137(79.2) | 95(81.2) |