Table 3 Relationships among expression of PD-L1, CD8, and PD-1 with deficient mismatch repair
Parameters | PD-L1 expression (%) | CD8 expression (%) | ||||||
|---|---|---|---|---|---|---|---|---|
Negative | Positive | P | Low | High | P | |||
CD8 expression | Low | 218 (71.5) | 87 (28.5) | < 0.001* | – | – | – | |
High | 83 (48.0) | 90 (52.0) | – | – | – | |||
PD-1 expression | Low | 214 (70.4) | 90 (29.6) | < 0.001* | 238 (78.8) | 64 (21.2) | < 0.001* | |
High | 88 (49.7) | 89 (50.3) | 67 (38.1) | 109 (61.9) | ||||
Deficient mismatch repair | Absence | 283 (64.2) | 158 (35.8) | 0.037* | 287 (65.4) | 152 (34.6) | 0.017* | |
Presence | 19 (47.5) | 21 (52.5) | 18 (46.2) | 21 (53.8) | ||||