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Table 3 Relationships among expression of PD-L1, CD8, and PD-1 with deficient mismatch repair

From: Immune classification for the PD-L1 expression and tumour-infiltrating lymphocytes in colorectal adenocarcinoma

ParametersPD-L1 expression (%)CD8 expression (%)
NegativePositiveP LowHighP
CD8 expressionLow218 (71.5)87 (28.5)<  0.001*
High83 (48.0)90 (52.0) 
PD-1 expressionLow214 (70.4)90 (29.6)<  0.001*238 (78.8)64 (21.2)<  0.001*
High88 (49.7)89 (50.3) 67 (38.1)109 (61.9) 
Deficient mismatch repairAbsence283 (64.2)158 (35.8)0.037*287 (65.4)152 (34.6)0.017*
Presence19 (47.5)21 (52.5) 18 (46.2)21 (53.8) 
  1. Cases without clinical information or with unassessable data due to cautery artifact, fragmentation, or incorrect orientation of tumour tissues are excluded from statistical analyses