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Fig. 1 | BMC Cancer

Fig. 1

From: Ovarian hyperstimulation closely associated with resumption of follicular growth after chemotherapy during tamoxifen treatment in premenopausal women with breast cancer: a multicenter retrospective cohort study

Fig. 1

Flow chart showing the study design and groups. Two hundred and seventy-one premenopausal patients, who received post-operative TAM therapy for endocrine-dependent breast cancer (stage 0 to IV) from April 2011 to March 2016, were recruited in this study. Among them, 36 cases were omitted by lack of data or follow up failed. The remaining patients (n = 235) were classified into 4 groups based on pre- or post-operative adjuvant therapies: group A (n = 26), treated with TAM alone; group B (n = 63), TAM treatment after 2-year-combined therapy with a Gn-RH agonist; group C (n = 110), TAM treatment after chemotherapy; group D (n = 36), 5-year-combined therapy with TAM and a Gn-RH agonist

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