Table 3 The enriched KEGG pathway terms of the DEGs
Pathway ID | Pathway Name | Gene Count | FDR | LogP | Genes |
|---|---|---|---|---|---|
hsa05150 | Staphylococcus aureus infection | 10 | 6.33E-13 | −15.21 | HLA-DQB1, C1QA, HLA-DRB4, HLA-DPA1, FCGR2A, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05332 | Graft-versus-host disease | 9 | 1.37E-12 | −14.85 | HLA-DQB1, CD86, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05330 | Allograft rejection | 9 | 3.67E-12 | −14.41 | HLA-DQB1, CD86, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa04940 | Type I diabetes mellitus | 9 | 1.11E-11 | −13.93 | HLA-DQB1, CD86, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa04672 | Intestinal immune network for IgA production | 9 | 2.96E-11 | −13.50 | HLA-DQB1, CD86, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05322 | Systemic lupus erythematosus | 11 | 3.85E-11 | −13.39 | HLA-DQB1, C1QA, CD86, HLA-DRB4, HLA-DPA1, FCGR2A, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05320 | Autoimmune thyroid disease | 9 | 7.06E-11 | −13.13 | HLA-DQB1, CD86, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05310 | Asthma | 8 | 1.49E-10 | −12.80 | HLA-DQB1, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05416 | Viral myocarditis | 9 | 1.54E-10 | −12.79 | HLA-DQB1, CD86, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05152 | Tuberculosis | 11 | 6.54E-10 | −12.16 | HLA-DQB1, HLA-DRB4, HLA-DPA1, FCGR2A, HLA-DMB, HLA-DOA, HLA-DMA, CD14, CD74, HLA-DQA1, HLA-DRA |
hsa05140 | Leishmaniasis | 9 | 9.79E-10 | −11.98 | HLA-DQB1, HLA-DRB4, HLA-DPA1, FCGR2A, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa04612 | Antigen processing and presentation | 9 | 1.73E-09 | −11.74 | HLA-DQB1, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, CD74, HLA-DQA1, HLA-DRA |
hsa05323 | Rheumatoid arthritis | 9 | 5.81E-09 | −11.21 | HLA-DQB1, CD86, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa04145 | Phagosome | 10 | 8.33E-09 | −11.06 | HLA-DQB1, HLA-DRB4, HLA-DPA1, FCGR2A, HLA-DMB, HLA-DOA, HLA-DMA, CD14, HLA-DQA1, HLA-DRA |
hsa05145 | Toxoplasmosis | 9 | 3.62E-08 | −10.42 | HLA-DQB1, HLA-DRB4, HLA-DPA1, ALOX5, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05321 | Inflammatory bowel disease (IBD) | 8 | 4.36E-08 | −10.34 | HLA-DQB1, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa04514 | Cell adhesion molecules (CAMs) | 9 | 2.86E-07 | −9.52 | HLA-DQB1, CD86, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05168 | Herpes simplex infection | 9 | 2.18E-06 | −8.64 | HLA-DQB1, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, CD74, HLA-DQA1, HLA-DRA |
hsa05164 | Influenza A | 8 | 5.24E-05 | −7.26 | HLA-DQB1, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05166 | HTLV-I infection | 8 | 7.01E-04 | −6.13 | HLA-DQB1, HLA-DRB4, HLA-DPA1, HLA-DMB, HLA-DOA, HLA-DMA, HLA-DQA1, HLA-DRA |
hsa05169 | Epstein-Barr virus infection | 5 | 0.13728 | −3.84 | HLA-DQB1, HLA-DRB4, HLA-DPA1, HLA-DQA1, HLA-DRA |
hsa04640 | Hematopoietic cell lineage | 3 | 14.8897 | −1.77 | HLA-DRB4, CD14, HLA-DRA |