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Fig. 2 | BMC Cancer

Fig. 2

From: Detection of early adenocarcinoma of the esophagogastric junction by spraying an enzyme-activatable fluorescent probe targeting Dipeptidyl peptidase-IV

Fig. 2

Fluorescence imaging with EP-HMRG of the tumor opening on the squamous epithelium. a Endoscopic imaging with white light before endoscopic submucosal dissection (ESD). b Magnifying narrow band imaging (M-NBI). c Endoscopic imaging with white light after ESD. The squamocolumnar junction (SCJ) is shown as a yellow line. d Fluorescence imaging after EP-HMRG spraying. e Pathological feature of the lesion extending under the squamous epithelium (hematoxylin and eosin staining). Arrows indicate the tumor opening on the squamous epithelium. Scale bars of (c and d), 5 mm. Scale bars of (e), 200 μm. The arrowheads of each color in (a–d) correspond to those of the same color in each case. The dotted circles indicate columnar epithelium without atypia (case #12)

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