Table 3 The diagnostic sensitivity and specificity of CTC, CEA, nodule type, nodule size and nodule site in patients with SPN.(N = 131)
Diagnostic method | Cutoff point | Sensitivity (%) | Specificity (%) | Youden Index value | AUC (95% CI) |
|---|---|---|---|---|---|
CEA (ng/ml) | 2.09 | 54.12 | 73.91 | 0.2803 | 0.626 (0.526–0.725) |
CTC (units) | 6 | 67.06 | 56.52 | 0.2358 | 0.780 (0.700–0.860) |
Size (mm) | 8 | 88.24 | 73.85 | 0.1432 | 0.572 (0.466–0.677) |
NT (HU) | −600 | 70.57 | 45.73 | 0.2489 | 0.626 (0.524–0.728) |
Site | 58.79 | 47.76 | 0.1109 | 0.555 (0.451–0.659) | |
CTC + CEA | 57.65 | 87.13 | 0.3688 | 0.734 (0.537–0.832) | |
CTC + CEA + NT | 92.94 | 50.02 | 0.4290 | 0.827 (0.752–0.901) | |
CTC + CEA + NT + Size+Site | 77.63 | 70.71 | 0.4829 | 0.841 (0.769–0.914) |