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Fig. 6 | BMC Cancer

Fig. 6

From: Elevated matrix metalloproteinase 7 expression promotes the proliferation, motility and metastasis of tongue squamous cell carcinoma

Fig. 6

MMP7 knockdown inhibits tongue cancer cell metastasis in vivo. a, Representative images of LN4 cells infected with lentiviral vectors or not are shown in a (left). The MMP7 mRNA expression levels of the negative control and MMP7-silenced groups were tested by quantitative real-time PCR (a, right). b, The effect of knocking down was confirmed by Western blotting analysis for these stabilized cell lines. Representative images of the tongue of nude mouse without or with tumour and metastasis lymph node from the neck, confirmed by HE simultaneously, are represented in c. The arrows in c (right) indicate metastatic lymph nodes. d, The statistical result of the lymph metastasis rate from each group is represented

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