Fig. 4

Inhibition of the expression of MMP7 suppresses the tongue cancer cell metastatic potential in vitro. a-b, Representative images of Transwell chambers coated without (upper panel) or with (upper panel) Matrigel after siRNA transfection, representing the migration and invasion abilities of the CAL27 and SCC9 cells. The number of cells crossing the Transwell chambers were counted. c-d, Representative photomicrographs (× 40) from the wound healing assay that monitored cell migration are shown. These experiments were repeated three times independently. *** p < 0.01