Fig. 2

Knockdown of MMP7 inhibits tongue cancer cell proliferation in vitro. a, The expression of MMP7 in CAL27 and SCC9 cells were detected by Western blotting. b-c, The MMP7 expression changes were confirmed by real-time PCR (b) and Western blotting (c) in the tongue cancer cells (CAL27 and SCC9) after transfecting siRNAs. d-e, The proliferation ability of tongue cancer cells was measured by the CCK8 assay (d, p < 0.01 from 72 h to 120 h) and colony formation assay (e) after knocking down MMP7. These experiments were repeated three times independently. * when p < 0.05, ** when p < 0.01, *** when p < 0.01