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Table 1 Patient Characteristics

From: Young-onset gastric cancer and Epstein–Barr Virus (EBV) – a major player in the pathogenesis?

Factor

Average Onset n = 35

Young Onset n = 39

p-value

Male sex, n(%)

20 (57%)

17 (43%)

NS

Family history of malignancy, n(%)

13 (48%)

13 (37%)

NS

Smoking history, n(%)

18 (49%)

18 (49%)

NS

HPpositive, n(%)

7 (47%)

8 (36%)

NS

Proximal tumor location, n(%)

11 (32%)

7 (22%)

NS

Signet ring cell, n(%)

13 (37%)

18 (55%)

NS

Stage IV at diagnosis, n(%)

3 (9%)

9 (27%)

P < 0.05

HER2 positive, n(%)

3 (9%)

2 (5%)

NS

EBV positive, n(%)

13 (33%)

4 (11%)

P < 0.05

Median OS, months

47.8 months

69.7 months

NS

  1. Abbreviations: HP Helicobacter Pylori, HER2 Human epidermal growth factor receptor 2, EBV Epstein–Barr Virus, OS overall survival
  2. Data was missing on smoking history (5 patients), H. pylori (37), tumor location (13), HER2 (8), stage at diagnosis (5)