Table 2 Top 10 upregulated and 10 downregulated circRNAs in MM patients compared to HCs
circRNA | Alias | Probe | Type | Chromosome | Start | End | Log2FC | P value | Adjusted P value | Gene Symbol | Trend |
|---|---|---|---|---|---|---|---|---|---|---|---|
hsa_circRNA_104700 | hsa_circ_0005273 | ASCRP004952 | exonic | chr8 | 141,710,989 | 141,716,304 | 3.409915 | 4.27E-05 | 0.002753 | PTK2 | UP |
hsa_circRNA_102913 | hsa_circ_0058058 | ASCRP003221 | exonic | chr2 | 216,177,220 | 216,190,861 | 2.939907 | 0.000842 | 0.01638 | ATIC | UP |
hsa_circRNA_104181 | hsa_circ_0077765 | ASCRP004454 | exonic | chr6 | 125,366,356 | 125,398,004 | 2.927002 | 0.000841 | 0.01638 | RNF217 | UP |
hsa_circRNA_100033 | hsa_circ_0009581 | ASCRP000423 | exonic | chr1 | 8,555,122 | 8,601,377 | 2.343938 | 0.002566 | 0.031823 | RERE | UP |
hsa_circRNA_103276 | hsa_circ_0064136 | ASCRP003574 | exonic | chr3 | 9,482,139 | 9,506,356 | 2.255827 | 2.83E-05 | 0.002231 | SETD5 | UP |
hsa_circRNA_101695 | hsa_circ_0007146 | ASCRP002042 | exonic | chr16 | 5,077,135 | 5,078,186 | 2.247917 | 0.000244 | 0.007711 | NAGPA | UP |
hsa_circRNA_104134 | hsa_circ_0004136 | ASCRP004407 | exonic | chr6 | 73,713,630 | 73,751,785 | 2.232947 | 9.65E-05 | 0.004596 | KCNQ5 | UP |
hsa_circRNA_104640 | hsa_circ_0001806 | ASCRP004893 | exonic | chr8 | 68,018,139 | 68,028,357 | 2.221722 | 0.00036 | 0.009799 | CSPP1 | UP |
hsa_circRNA_100542 | hsa_circ_0017639 | ASCRP000922 | exonic | chr10 | 7,290,509 | 7,327,916 | 2.132697 | 6.32E-05 | 0.003752 | SFMBT2 | UP |
hsa_circRNA_101287 | hsa_circ_0008274 | ASCRP001647 | exonic | chr13 | 96,485,180 | 96,489,456 | 2.118815 | 0.004029 | 0.041781 | UGGT2 | UP |
hsa_circRNA_105034 | hsa_circ_0001947 | ASCRP005281 | exonic | chrX | 147,743,428 | 147,744,289 | −4.46399 | 3.17E-06 | 0.000578 | AFF2 | DOWN |
hsa_circRNA_104980 | hsa_circ_0001910 | ASCRP005227 | exonic | chrX | 10,031,484 | 10,066,619 | −4.12073 | 4.21E-07 | 0.000174 | WWC3 | DOWN |
hsa_circRNA_101280 | hsa_circ_0000497 | ASCRP001641 | exonic | chr13 | 78,293,666 | 78,327,493 | −3.99021 | 2.15E-07 | 0.000126 | SLAIN1 | DOWN |
hsa_circRNA_100526 | hsa_circ_0004277 | ASCRP000907 | exonic | chr10 | 1,125,950 | 1,126,416 | −3.95344 | 1.73E-07 | 0.000126 | WDR37 | DOWN |
hsa_circRNA_100527 | hsa_circ_0017446 | ASCRP000908 | exonic | chr10 | 1,125,950 | 1,132,297 | −3.95022 | 2.21E-07 | 0.000126 | WDR37 | DOWN |
hsa_circRNA_103106 | hsa_circ_0007609 | ASCRP003410 | exonic | chr20 | 62,559,687 | 62,562,375 | −3.8805 | 2.07E-07 | 0.000126 | DNAJC5 | DOWN |
hsa_circRNA_103765 | hsa_circ_0071375 | ASCRP004055 | exonic | chr4 | 166,141,085 | 166,184,511 | −3.31029 | 5.36E-06 | 0.000749 | KLHL2 | DOWN |
hsa_circRNA_101648 | hsa_circ_0000651 | ASCRP001997 | exonic | chr15 | 90,982,563 | 90,986,710 | −3.28088 | 3.21E-07 | 0.000163 | IQGAP1 | DOWN |
hsa_circRNA_100731 | hsa_circ_0020594 | ASCRP001105 | exonic | chr11 | 133,583 | 134,947 | −3.25608 | 0.000108 | 0.004888 | AL137655 | DOWN |
hsa_circRNA_104689 | hsa_circ_0001824 | ASCRP004941 | exonic | chr8 | 131,164,981 | 131,181,313 | −3.24653 | 2.21E-07 | 0.000126 | ASAP1 | DOWN |