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Table 1 Patient Characteristics

From: Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer

Characteristic

High

Low

P value

Gender, n

 RSC

156

96

0.3637

  Male

77

54

 

  Female

77

42

 

 LSC

68

106

0.1231

  Male

41

51

 

  Female

27

55

 

 REC

63

91

0.5118

  Male

37

48

 

  Female

26

43

 

MS, n

 RSC

156

96

< 0.0001*

  MSS/MSI-L

92

89

 

  MSI-H

64

7

 

 LSC

68

106

0.0771

  MSS/MSI-L

64

105

 

  MSI-H

4

1

 

 REC

63

91

0.0264*

  MSS/MSI-L

59

91

 

  MSI-H

4

0

 

Age,Mean ± SD

 RSC

70 ± 13.69

67 ± 12.95

0.2222

 LSC

66 ± 11.11

64 ± 13.07

0.4267

 REC

64 ± 10.56

65 ± 12.32

0.81

Pathologic stage, n (%)

 RSC

156

96

0.0278*

  I

33(21.2%)

11(11.5%)

 

  II

73(46.8%)

38(39.6%)

 

  III

38(24.4%)

32(33.3%)

 

  IV

12(7.7%)

15(15.6%)

 

 LSC

68

106

0.1374

  I

12(17.6%)

17(16.0%)

 

  II

26(38.2%)

33(31.1%)

 

  III

23(33.8%)

30(28.3%)

 

  IV

7(10.3%)

26(24.5%)

 

 REC

63

91

 

  I

10(15.9%)

20(22.0%)

0.0279*

  II

29(46.0%)

21(23.1%)

 

  III

17(27.0%)

33(36.3%)

 

  IV

7(11.1%)

17(18.7%)

 
  1. RSC Right-sided colon cancer, LSC Left-sided colon cancer, REC Rectal cancer, MSS Microsatellite stable, MSI-L Microsatellite instability-low, MSI-H Microsatellite instability-high
  2. *Indicates statistically significant difference (p < 0.05)