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Fig. 1 | BMC Cancer

Fig. 1

From: Immunogenomic pathways associated with cytotoxic lymphocyte infiltration and survival in colorectal cancer

Fig. 1

An outline of the methods and organization of this study. This flowchart describes the process and breakdown of patients into anatomical location groups and pathological stages based on cytotoxic lymphocytes (CL) abundance score. After dividing patients into anatomical groups and stages, we then compared CL-High and CL-Low to determine differential expressed genes (DEGs). Pathway enrichment and Survival analysis was then undertaken using identified DEGs. Pathway associations were determined for DEGs using the Reactome online browser. CL, cytotoxic lymphocytes; COAD, colon adenocarcinoma; READ, rectal adenocarcinoma; DEG, Differentially Expressed Gene; Nc, the number of cases; Ng, the number of genes; RSC, right-sided colon cancer; LSC, left-sided colon cancer; REC, rectal cancer

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