Table 1 Clinical characteristics of B-ALL patients
1─17 yo | 18─65 yo | All | p-Value | |
|---|---|---|---|---|
Age groups | ||||
Number of patients | 122 (76.3%) | 38 (23.7%) | 160 (100%) | |
Median age (range) | 4 (1–17) | 32 (18–65) | 5 (1–65) | |
Sex: | ||||
Male | 69 (56.6%) | 15 (39.5%) | 84 (52.5%) | 0.093 |
Female | 53 (43.4%) | 23 (60.5%) | 76 (47.5%) | |
Risk group: | ||||
SR | 72 (59.5%) | 7 (18.4%) | 79 (49.7%) | < 0.001 |
IR | 38 (31.4%) | 17 (44.7%) | 55 (34.6%) | |
HR | 5 (4.1%) | 6 (15.8%) | 11 (6.9%) | |
HR-SCT | 3 (2.5%) | 5 (13.2%) | 8 (5%) | |
Induction failure | 3 (2.5%) | 3 (7.9%) | 6 (3.8%) | |
Not risk grouped | 1 | 0 | 1 | |
Induction: | ||||
Prednisolone | 113 (92.6%) | 30 (78.9%) | 143 (89.4%) | 0.030 |
Dexamethasone | 9 (7.4%) | 8 (21.1%) | 17 (10.6%) | |
WBC (× 109/l): | ||||
< 100 | 113 (92.6%) | 30 (78.9%) | 143 (89.4%) | 0.030 |
≥ 100 | 9 (7.4%) | 8 (21.1%) | 17 (10.6%) | |
WBC median (range) | 14 (1–641) | 10.5 (0.9–481.9) | 13.5 (0.9–641) | 0.672 |
Hgb (g/l) median (range) | 83 (24–140) | 90.5 (52–142) | 84 (24–142) | 0.117 |
Platelets median (range) | 62 (0–457) | 37 (5–320) | 54.5 (0–457) | 0.075 |
CNS Status: | ||||
CNS1 | 104 (85.2%) | 33 (86.8%) | 137 (85.6%) | 0.281 |
CNS2 | 14 (11.5%) | 2 (5.3%) | 16 (10%) | |
CNS3 | 4 (3.3%) | 3 (7.9%) | 7 (4.4%) | |