Changes in cerebrospinal fluid interleukin-10 levels display better performance in predicting disease relapse than conventional magnetic resonance imaging in primary central nervous system lymphoma

Table 1 The interval of IL-10 relapse and MRI relapse

Case No.	Lesion location	The time point of IL-10 relapse				PFS by MRI scan(days)	The interval of IL-10 relapse and MRI relapse (days)
Case No.	Lesion location	Treatment state	PFS by IL-10 relapse (days)	CSF IL-10 (pg/ml)	Disease status based on MRI	PFS by MRI scan(days)	The interval of IL-10 relapse and MRI relapse (days)
2	CNS	Follow	210	10.4	PR	303	93
15	CNS	Follow	745	145	PR	1147	402
27	CNS+EYE	Induc	108	27.5	PR	140	32
29	CNS+EYE	Follow	372	28.8	CR	438	66
33	CNS	Induc	102	10.2	CR	130	28
40	CNS	Induc	67	74	PR	119	52
39	CNS	Induc	249	206	PR	300	51
42	PVRL	Follow	209	13.6	CR	298	89
41	PVRL	Follow	246	56.6	CR	387	141
47	PVRL	Induc	119	15.6	CR	187	68

Abbreviations: CNS central nerves system, CR complete remission, Follow follow-up phase, Induc induction phase, PVRL primary vitreoretinal lymphoma, PR partial remission

ISSN: 1471-2407