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Table 1 Demographic and clinical characteristics of 141 colorectal cancer patients

From: Comparison of long-term outcomes between Lynch sydrome and sporadic colorectal cancer: a propensity score matching analysis

Variables

LS group

(N = 47)

SCRC group

(N = 94)

χ2 value

p value

Age (years)

  

0.070

0.792

 <  50

35(74.5%)

68(72.3%)

  

 ≥50

12(2.5.5%)

26(27.7)

  

Gender

  

0.058

0.810

 Male

26(55.3%)

54(57.4%)

  

 Female

21(44.7%)

40(42.6%)

  

CEA (ng/ml)

  

0.104

0.747

 ≥5.2

7(14.9%)

16(17.0%)

  

 < 5.2

40(85.1%)

78(83.0%)

  

Location

  

3.177

0.365

 Right colon

18(38.3%)

40(42.6%)

  

 Left colon

20(42.6%)

41(43.6%)

  

 Rectal

5(10.6%)

11(11.7%)

  

 Multiple

4(8.5%)

2(2.1%)

  

Tumor size a (cm)

5.17±2.61

5.21±2.79

0.106

0.754

Pathological classification

  

0.474

0.789

 Adenocarcinoma

34(72.3%)

71(75.5%)

  

 Partial mucinous

5(10.7%)

11(11.7%)

  

 Mucinous adenocarcinoma

8(17.0%)

12(12.8%)

  

Differentiation grade

  

0.259

0.878

 Well

1(2.1%)

1(1.1%)

  

 Moderately

28(59.6%)

56(59.5%)

  

 Poorly

18(38.3%)

37(39.4%)

  

Cancerous node

  

0.534

0.465

 Occurrence

2(4.3%)

7(7.4%)

  

 Absence

45(95.7%)

87(92.6%)

  

Vascular invasion

  

0.534

0.461

 Occurrence

8(17.0%)

21(22.3%)

  

 Absence

39(83.0%)

73(77.7%)

  

Perineural invasion

  

0.252

0.616

 Occurrence

6(12.8%)

15(16.0%)

  

 Absence

41(87.2%)

79(84.0%)

  

T stage

  

0.130

0.937

 T1

7(14.9%)

12(12.8%)

  

 T2

8(17.0%)

17(18.1%)

  

 T3

32(68.1%)

65(69.1%)

  

N stage

  

1.840

0.399

 N0

34(72.3%)

57(60.6%)

  

 N1

9(19.1%)

23(24.5%)

  

 N2

4(8.6%)

14(14.9%)

  

Metastasis

  

0.265

0.607

 Occurrence

2(4.3%)

6(6.4%)

  

 Absence

45(95.7%)

88(93.6%)

  

TNM stage

  

1.200

0.753

 I

13(27.7%)

27(28.7%)

  

 II

17(36.2%)

30(31.9%)

  

 III

15(31.8%)

31(33.0%)

  

 IV

2(4.3%)

6(6.4%)

  

KRAS mutant

21(44.6%)

49 (52.1%)

0.695

0.404

NRAS mutant

2(4.3%)

3 (3.2%)

0.104

0.747

Adjuvant chemotherapy

  

1.420

0.233

 Received

26(55.3%)

42(44.7%)

  
  1. CEA Carcinoembryonic antigen, LS Lynch syndrome, SCRC Sporadic colorectal cancer