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Fig. 5 | BMC Cancer

Fig. 5

From: LncRNA WT1-AS downregulates lncRNA UCA1 to suppress non-small cell lung cancer and predicts poor survival

Fig. 5

WT1-AS downregulated UCA1 to inhibit NSCLC cell proliferation, invasion and migration. WT1-AS downregulated UCA1 to suppress NSCLC cell proliferation (a). Cell proliferation assay was performed to assess the effects of the overexpression of WT1-AS and UCA1 on the proliferation of NSCLC cells. Mean values of 3 biological replicates are presented (*p < 0.05). Transwell assay showed that UCA1 overexpression promoted, while WT1-AS overexpression inhibited invasion (b) and migration (c) of NSCLC cells. In addition, the role of WT1-AS overexpression was inhibited by the overexpression of UCA1. Mean values of 3 biological replicates are presented. Scale bar represent 100 μm. NC, cells transfected with empty vector; C, untransfected cell. *, p < 0.05

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