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Table 4 Baseline characteristics of patients with EGC and their difference in terms of depth of invasion following ESD procedure

From: Clinico-pathologic determinants of non-e-curative outcome following en-bloc endoscopic submucosal dissection in patients with early gastric neoplasia

Patient Parameters

All EGCs lesions (n = 162)

[No. (%)]

Mucosal lesion

(n = 132)

[No. (%)]

Submucosal

(n = 30)

[No. (%)]

p*-value

Mean age in years (±SD)

61.10 (± 8.76)

60.33 (± 8.38)

64.53 (± 9.70)

0.563

Gender

   

0.981

 Female

42 (25.9)

34 (25.8)

8 (26.7)

 

 Male

120 (74.1)

98 (74.2)

22 (73.3)

 

Tumor location

   

<  0.001

 Lower third

95 (58.6)

89 (67.4)

6 (20.0)

 

 Middle or Upper third

67 (41.4)

43 (32.6)

24 (80.0)

 

Gross tumor type

   

0.013

 Group 1

46 (28.4)

43 (32.6)

3 (10.0)

 

 Group 2

116 (71.6)

89 (67.4)

27 (90.0)

 

Ulceration status

   

0.001

 Absent

135 (83.3)

116 (87.9)

19 (63.3)

 

 Present

27 (16.7)

16 (12.1)

11 (36.7)

 

Size of tumor in

   

0.001

 ≤2 cm

111 (68.5)

98 (74.2)

13 (43.3)

 

 > 2 cm

51 (31.5)

34 (25.8)

17 (56.7)

 

Differentiation

   

<  0.001

 Differentiated

129 (79.6)

114 (86.4)

15 (50.0)

 

 Undifferentiated

33 (20.4)

18 (13.6)

15 (50.0)

 

Horizontal margin

   

0.088

 Negative

159 (98.1)

131 (99.2)

28 (91.7)

 

 Positive

3 (1.9)

1 (0.8)

2 (8.3)

 

Vertical margin

   

0.001

 Negative

158 (97.5)

132 (100)

26 (86.7)

 

 Positive

4 (2.5)

0 (0.0)

4 (13.3)

 

Lympho-vascular invasion

   

<  0.001

 Absent

159 (98.1)

132 (100)

27 (90.0)

 

 Present

3 (1.9)

0 (0.0)

3 (10.0)

 
  1. ESD Endoscopic Submucosal Dissection, EGC Early Gastric Cancers, Group 1 = lesions with Protruding (0-I), Purely superficial flat (0-IIb) and Mixed variants with 0-IIb predominant, Group 2 = Purely superficial elevated (0-IIa) or depressed (0-IIc) or mixed variants with either 0-IIa or 0-IIc predominant
  2. *Chi-squared independent test/Fisher’s exact test of probability or Student t-test