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Fig. 6 | BMC Cancer

Fig. 6

From: Development of an engineered peptide antagonist against periostin to overcome doxorubicin resistance in breast cancer

Fig. 6

PN expression and clinical significance in BCA patients. a Comparison of serum PN levels between BCA patients and normal controls. BCA patients n = 83, normal controls n = 60. b-c Tissue expression of PN in BCA tissue. PN staining presented only in stromal area but not cancer cells. b Low expression of PN, Q-score = 1 and (c) High expression of PN in patient with highest serum PN level, Q-score = 6. Original magnification was 200X. Scale bar represented 200 μm length. d-e Survival analysis of high PN expression compared with low PN expression in BCA patients from online database analyzed by Kaplan-Meier Plotter online tool (https://kmplot.com/). d Analysis using Liu_2014 data (n = 125) [40]. e Analysis using Tang_2018 data (n = 65) [41]

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BMC Cancer

ISSN: 1471-2407

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